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folinic

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folinic
folinic, a. Biochem. (fəʊˈlɪnɪk, fɒl-) [f. folic a. + -in + -ic.] folinic acid: a derivative of folic acid, believed to be the form in which the latter acts as a coenzyme.1949 T. J. Bond et al. in Jrnl. Amer. Chem. Soc. LXXI. 3852/2 On the basis of structure and functional relationship to folic acid... Oxford English Dictionary
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Folinic acid
This is the classical view of folinic acid rescue therapy. Folinic acid has dextro- and levorotary isomers. wikipedia.org
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FOLFIRI
It is made up of the following drugs: FOL – folinic acid (leucovorin), a vitamin B derivative with multiple applications, which in this context increases Regimen The regimen consists of: irinotecan (180 mg/m2 IV over 90 minutes) concurrently with folinic acid (400 mg/m2 [or 2 x 250 mg/m2] IV over 120 minutes wikipedia.org
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citrovorum
citrovorum (sɪˈtrəʊvərəm) [f. mod.L. Leuconostoc citrovorum, f. citr- + -vorum, neut. sing. of L. -vorus -vorous.] Esp. in citrovorum factor, the active form of folic acid; folinic acid.1948 Sauberlich & Baumann in Jrnl. Biol. Chem. Oct. 168 The ‘citrovorum unit’ was designated as the amount of subs... Oxford English Dictionary
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FOLFOX
Folinic acid is given concurrently. This is followed by an injection of fluorouracil into the cannula or central line. On the second day, folinic acid is given as an injection or via IV drip for 2 hours. wikipedia.org
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leucovorin
leucovorin Biochem. (l(j)uːˈkɒvərɪn) [f. mod.L. Leuco(nostoc (f. Gr. λευκο- leuco- + nostoc), the generic name + citro)vor(um (f. citr-, citro- + L. vor-āre to devour + -um) the specific epithet, of the bacterium whose growth it was originally found to promote: see -in1.] = folinic acid.1951 H. P. B... Oxford English Dictionary
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5-formyltetrahydrofolate cyclo-ligase
In enzymology, a 5-formyltetrahydrofolate cyclo-ligase () is an enzyme that catalyzes the chemical reaction ATP + 5-formyltetrahydrofolate (folinic acid wikipedia.org
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IFL (chemotherapy)
IFL is a chemotherapy regimen for treatment of certain cancers, consisting of concurrent treatment with irinotecan, leucovorin (folinic acid), and fluorouracil wikipedia.org
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5,10-methenyltetrahydrofolate synthetase deficiency
However, contrary to other causes of cerebral folate deficiency, the use of folinic acid for treatment may be contraindicated due to excess levels of folinic wikipedia.org
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Glucarpidase
The main antidote for methotrexate overdoses prior to the approval of this drug were high doses of folinic acid. Glucarpidase also degrades folinic acid so the two should not be used together (within two hours of one another). wikipedia.org
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Cerebral folate deficiency
Over time, the treatment with folinic acid has shown to reduce a variety of symptoms of CFD. Treatment requires taking folinic acid for a significant period of time. wikipedia.org
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C20H23N7O7
The molecular formula C20H23N7O7 (molar mass: 473.44 g/mol, exact mass: 473.1659 u) may refer to: Folinic acid 10-Formyltetrahydrofolate (10-CHO-THF wikipedia.org
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Pyrimethamine
Medical uses Pyrimethamine is typically given with a sulfonamide and folinic acid. Other medications Pyrimethamine is typically given with folinic acid and sulfadiazine. wikipedia.org
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卵巢肌肉来源肿瘤的西医治疗
可加用亚叶酸(四氢叶酸，folinic acid)、甲氨蝶呤(methotrexate)、多柔比星(阿霉素)。
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Dihydrofolate reductase deficiency
Treatment Folinic acid, a reduced form of folate, is used to correct the reduced 5-MTHF levels in the cerebrospinal fluid and the anemia. wikipedia.org
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