folinic, a. Biochem.
(fəʊˈlɪnɪk, fɒl-)
[f. folic a. + -in + -ic.]
folinic acid: a derivative of folic acid, believed to be the form in which the latter acts as a coenzyme.
| 1949 T. J. Bond et al. in Jrnl. Amer. Chem. Soc. LXXI. 3852/2 On the basis of structure and functional relationship to folic acid, this active principle has been termed folinic acid. 1962 New Scientist 17 May 364/3 To counter⁓act the damaging effects of the methotrexate that spilled over into the general circulation, a biological antagonist, folinic acid (leucovorin), was injected intramuscularly. 1966 E. S. West et al. Textbk. Biochem. (ed. 4) xviii. 814 Folinic acid, citrovorum factor (CF), and leucovorin are names for a naturally occurring derivative of folic acid... It is N5-formyl-5,6,7,8-tetrahydropteroylglutamic acid. |