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cobalamin

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cobalamin
cobalamin Biochem. (kəʊˈbɒləmɪn) [f. cobalt + vitamin.] A name given orig. to the characteristic part of the vitamin B12 molecule (see quot. 1950), and hence used for any member of the vitamin B12 group, each of which contains this part in its molecule.1950 E. A. Kaczka et al. in Science 29 Sept. 35... Oxford English Dictionary
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Cobalamin riboswitch
to cobalamin binding. Cobalamin riboswitches can exhibit selectivity toward different forms of cobalamin. wikipedia.org
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Cobalamin biosynthesis
Cobalamin biosynthesis is the process by which bacteria and archea make cobalamin, vitamin B12. from cobalamin. wikipedia.org
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cyanocobalamin
ˌcyanocoˈbalamin Biochem. [f. cyano- + cobalamin.] Vitamin B12.1950 [see cobalamin]. 1961 Lancet 26 Aug. 482/2 It seems probable that the pharmacopœial term ‘vitamin B 12’, at present restricted..to cyanocobalamin, will soon have to be extended to include also hydroxocobalamin. 1962 New Scientist 15... Oxford English Dictionary
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Cobalt chelatase
This enzyme is part of the biosynthetic pathway to cobalamin (vitamin B12) in aerobic bacteria. See also Cobalamin biosynthesis References Further reading EC 6.6.1 wikipedia.org
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hydroxocobalamin
hydroxocobalamin Biochem. (haɪˌdrɒksəʊkəʊˈbɒləmɪn) [f. hydroxo- + cobalamin.] An analogue of cyanocobalamin (vitamin B12) in which the cyanide ion is replaced by a hydroxide (OH-) ion.1950 [see cobalamin]. 1961 Lancet 26 Aug. 483/1 For the treatment of pernicious anæmia hydroxocobalamin appears to b... Oxford English Dictionary
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Transcobalamin
Transcobalamins are carrier proteins which bind cobalamin (B12). It primarily serves to protect cobalamin (Vitamin B12) from acid degradation in the stomach by producing a Haptocorrin-Vitamin B12 complex. wikipedia.org
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MMACHC
This function has also been attributed to cobalamin reductases. The MMACHC gene product and cobalamin reductases enable the interconversion of cyano- and alkylcobalamins. wikipedia.org
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Sirohydrochlorin cobaltochelatase
cobaltochelatase (EC 4.99.1.3) catalyzes the reaction cobalt-sirohydrochlorin + 2 H+ = sirohydrochlorin + Co2+ In the forward direction of reactions towards cobalamin This enzyme is part of the biosynthetic pathway to cobalamin (vitamin B12) in bacteria such as Salmonella typhimurium and Bacillus megaterium. wikipedia.org
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MMACHC
MMACHC (Methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria) هوَ بروتين يُشَفر بواسطة جين MMACHC في الإنسان. wikipedia.org
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Cob(I)yrinic acid a,c-diamide adenosyltransferase
AdoCbl contains an adenosyl moiety liganded to the cobalt ion of cobalamin via a covalent Co-C bond. Cobalamin biosynthesis References Protein families EC 2.5.1 wikipedia.org
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MMAA
MMAA (Methylmalonic aciduria (cobalamin deficiency) cblA type) هوَ بروتين يُشَفر بواسطة جين MMAA في الإنسان. wikipedia.org
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MMADHC
Vitamin B12 (cobalamin) is essential for normal development and survival in humans. References External links GeneReviews/NCBI/NIH/UW entry on Disorders of Intracellular Cobalamin Metabolism PDBe-KB provides an overview of all the wikipedia.org
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Adenosylcobinamide-GDP ribazoletransferase
Adenosylcobinamide-GDP ribazoletransferase (, CobS, cobalamin synthase, cobalamin-5'-phosphate synthase, cobalamin (5'-phosphate) synthase) is an enzyme See also Cobalamin biosynthesis References External links EC 2.7.8 wikipedia.org
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Methionine synthase
Many different microorganisms express both the cobalamin-dependent and cobalamin-independent forms. Both the cobalamin-dependent and cobalamin-independent forms of the enzyme carry out the same overall chemical reaction, the transfer of a methyl group wikipedia.org
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