monosomic, a. (n.) Cytology.
(mɒnəʊˈsəʊmɪk)
[f. monosome + -ic.]
Having or being a diploid chromosome complement in which one (or occas. more than one) chromosome lacks its homologous partner. Hence as n., a monosomic individual.
| 1926 Univ. Calif. Publ. Bot. XI. 61 This paper is devoted to a second form called ‘fluted’, which has been found on cytological examination to be a monosomic (2n – 1). Ibid. 67 Monosomic forms may be used advantageously for a determination of linkage groups. 1932 Genetics XVII. 689 Comparatively few investigations have been concerned with a study of monosomics (2n – 1 types) and their mode of inheritance. 1957 C. P. Swanson Cytol. & Cytogenetics (1958) vi. 190 Probably the best known monosomic type is the haplo-IV Drosophila. 1961 Lancet 23 Sept. 723/2 The normal male is naturally monosomic for the X, and the XO-female can reach maturity in reasonably good health. 1972 Hereditas LXX. 132/1 A number of monosomic lines of Chinese Spring were used as pollen parents. 1974 Nature 19 Apr. 714/3 Monosomics and trisomics have seldom been developed in the same species. |
So ˈmonosomy, the character or condition of having a monosomic chromosome complement.
| 1948 Nature 5 June 873/1 Genetical experience shows that, like polyploidy, monosomy and polysomy in a wide range of plants and animals can characterize whole individuals. 1961 Lancet 16 Sept. 625/1 Both cases show monosomy and trisomy involving the X chromosome or an autosome of similar size and morphology. 1972 Science 5 May 518/3 Not so well documented..are the occasional observations of monosomy, trisomy and other aneuploidies. |