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piperazine
piperazine Pharm. (pɪˈpɛrəziːn, formerly ˈpɪpərəzaɪn) [First formed as G. piperazin (A. T. Mason 1887, in Ber. d. Deut. Chem. Ges. XX. 267), f. piper(idin piperidine + azin azine.] A colourless, crystalline, heterocyclic base, C4H10N2 which is used, in the form of a salt or hydrate, as an anthelmint...
Oxford English Dictionary
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Piperazine
Piperazine hydrate, piperazine adipate and piperazine citrate (used to treat ascariasis and enterobiasis) are the most common anthelmintic piperazine compounds Piperazine derivatives as drugs
Many currently notable drugs contain a piperazine ring as part of their molecular structure.
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1-(2-Diphenyl)piperazine
1-(2-Diphenyl)piperazine, also known as RA-7, is a drug which acts as a potent and selective antagonist at the 5HT serotonin receptor.
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Substituted piperazine
Substituted piperazines are a class of chemical compounds based on a piperazine core. (1-NP)
1-(2-Pyrimidinyl)piperazine (1-PP)
ORG-12962 (1-(5-trifluoromethyl-6-chloropyridin-2-yl)piperazine)
Quipazine (2-piperazin-1-ylquinoline)
Many
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hydroxyzine
hydroxyzine Pharm. (haɪˈdrɒksɪziːn) [f. hydroxy- + piperazine.] A tranquillizing drug which is usu. administered as the hydrochloride, a white bitter-tasting powder, and is a complex derivative of piperazine.1956 Jrnl. Amer. Med. Assoc. 16 June 604/1 Hydroxyzine (Atarax) hydrochloride is a new tranq...
Oxford English Dictionary
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1-(4-(Trifluoromethyl)phenyl)piperazine
1-[4-(Trifluoromethyl)phenyl]piperazine is a serotonergic releasing agent. See also
Substituted piperazine
References
Phenylpiperazines
Serotonin receptor agonists
Serotonin releasing agents
Trifluoromethyl compounds
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1-(3-Chlorophenyl)-4-(2-phenylethyl)piperazine
1-(3-Chlorophenyl)-4-(2-phenylethyl)piperazine (3C-PEP) is a designer drug of the piperazine class of chemical substances. 3C-PEP is related to meta-cholorophenylpiperazine It was first described in 1994 in a patent disclosing a series of piperazine compounds as sigma receptor ligands.
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Befuraline
Befuraline (DIV-154) is a psychoactive drug and member of the piperazine chemical class which was developed in Germany in the 1970s. See also
Substituted piperazine
Fipexide
Piberaline
References
Anthelmintics
Piperazines
Benzofuran-2-carboxamides
Serotonin-norepinephrine-dopamine
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Methylenedioxybenzylpiperazine
1-(3,4-Methylenedioxybenzyl)piperazine (MDBZP, piperonylpiperazine) is a chemical compound of the piperazine chemical class related to benzylpiperazine See also
3,4-Methylenedioxy-N-methylamphetamine (MDMA)
Substituted piperazine
References
External links
Benzodioxoles
Designer drugs
1-Piperazinyl
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Pyridinylpiperazine
1-(2-Pyridinyl)piperazine is a chemical compound and piperazine derivative. Some derivatives of this substance are known to act as potent and selective α2-adrenergic receptor antagonists, such as 1-(3-fluoro-2-pyridinyl)piperazine
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Diphenylmethylpiperazine
Diphenylmethylpiperazine, also known as benzhydrylpiperazine, is a chemical compound and piperazine derivative. It features a piperazine ring with a benzhydryl (diphenylmethyl) group bound to one of the nitrogens.
References
1-Piperazinyl compounds
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Piberaline
Piberaline (EGYT-475; Trelibet) is a psychoactive drug and member of the piperazine chemical class which was developed in the 1980s. See also
Substituted piperazine
Befuraline
Fipexide
References
Piperazines
Carboxamides
2-Pyridyl compounds
Serotonin-norepinephrine-dopamine releasing
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Aminoethylpiperazine
Aminoethylpiperazine (AEP) is a derivative of piperazine. These include ethylenediamine, diethylenetriamine, triethylenetetramine, tetraethylenepentamine, other higher homologues and aminoethyl piperazine.
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Pyrimidinylpiperazine
1-(2-Pyrimidinyl)piperazine (1-PP, 1-PmP) is a chemical compound and piperazine derivative. See also
Substituted piperazine
Pyridinylpiperazine
Phenylpiperazine
Diphenylmethylpiperazine
Benzylpiperazine
References
5-HT1A agonists
Alpha-
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Para-Methoxyphenylpiperazine
para-Methoxyphenylpiperazine (MeOPP, pMPP, 4-MPP; Paraperazine) is a piperazine derivative with stimulant effects which has been sold as an ingredient See also
Substituted piperazine
Acta Crystallogr. (2020).
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