Artificial intelligent assistant

missense

answer Answers

ProphetesAI is thinking...

MindMap

Sources

1
missense
ˈmissense, a. Biol. [mis-1 4.] Causing or involving the insertion of a different amino-acid at a particular point in a polypeptide or protein molecule from that which is usual.1961 Levinthal & Davison in Ann. Rev. Biochem. XXX. 651 An alteration in any base pair by a mutagen raises the possibility o... Oxford English Dictionary
prophetes.ai 0.0 3.0 0.0
2
Missense mRNA
Missense mRNA molecules are created when template DNA strands or the mRNA strands themselves undergo a missense mutation in which a protein coding sequence Biogenesis A missense mRNA arises from a missense mutation, in the event of which a DNA nucleotide base pair in the coding region of a gene is changed wikipedia.org
en.wikipedia.org 0.0 1.5 0.0
3
Missense mutation
Missense mutation is a type of nonsynonymous substitution in a DNA sequence. Not all missense mutations lead to appreciable protein changes. wikipedia.org
en.wikipedia.org 0.0 0.90000004 0.0
4
Location of TFBS in genome I have an annotated set of SNPs and I would like to explore the difference in the binding affinity of the transcription factor (TF) if I have a SNP in my locus. As my SNPs are annotated (I k...
I would link your data with the ENCODE dataset. This dataset provides locations of TFBS. It is also accessible via the UCSC genome browser. For the actual question TFBS are located pretty much everywhere, including exons (as described here), introns and of course intergenic regions (e.g. enhancers, ...
prophetes.ai 0.0 0.6 0.0
5
Sex-linked barring
The missense mutations in the B1 and B2 allele, however, have an opposite effect. Both missense mutations lead to a malfunctioning ARF protein, which is counteracting the effect of the higher activity of the gene to some degree. wikipedia.org
en.wikipedia.org 0.0 0.6 0.0
6
Point mutation vs Indels DNA sequence of a gene can be altered in a number of ways. Gene mutations have varying effects on health, depending on where they occur and whether they alter the function of essential protein...
A point mutation is a mutation causing the substitution, insertion or deletion of a single nucleotide. An indel is a change in the number of nucleotides (either through insertion or deletion hence the name). When talking about indel most people (in evolutionary biology at least) refer to the inserti...
prophetes.ai 0.0 0.3 0.0
7
Paul W. Sternberg
They used CRISPR-Cas9 to generate C. elegans equivalent human missense mutants. They compared the phenotypes from the missense mutants to the wildtype and known loss-of-function mutant controls in the autism-associated missense alleles wikipedia.org
en.wikipedia.org 0.0 0.3 0.0
8
Identifying mutations in a yeast strain > Cells of a triple-mutant yeast strain (leu- his- trp-) were spread either on minimal medium or on minimal medium supplemented with various combinations of histidine, leucine, ...
For starters, you can just google "confluent". It means that there are no colonies, but that the cells cover the whole plate. So when you provide all three amino acids, the cells fill up the whole plate. If you leave His out, but keep the plate at 25 degrees, the plate still fills up with cells, so ...
prophetes.ai 0.0 0.3 0.0
9
Birk-Barel syndrome
Gene Involved KCNK9 gene on chromosome 8 Type of mutation Missense mutation in the maternal copy of the KCNK9 gene Location on Chromosome 8q24.3 - Spectrum of disease caused by genetics All of the individuals have a missense mutation but the location of the missense mutation determines the severity wikipedia.org
en.wikipedia.org 0.0 0.3 0.0
10
MACHINE LEARNING Accurate proteome-wide missense variant effect ... - AAAS
Sep 19, 2023Andrew W. Senior, John Jumper, Demis Hassabis, Pushmeet Kohli*, Žiga Avsec* INTRODUCTION: Genome sequencing has re-vealed extensive genetic variation in human populations. Missense variants are genetic var-iantsthatalterthe amino acid sequence of pro-teins. Pathogenic missense variants disrupt protein function and reduce organismal fitness,
www.science.org 0.0 0.3 0.0
11
Adolescent idiopathic scoliosis
Ile107Leu) at chr15:48 902 952 T>G missense mutation (p.Asn280Thr) at chr15:48 826 300 T>C missense mutation (p.Gln697Arg) at chr15:48 796 007 T>G missense missense mutation (p.  wikipedia.org
en.wikipedia.org 0.0 0.0 0.0
12
点突变
错义突变（missense mutation）：使密码所对应的氨基酸改变。 （silent mutation）：密码改变，但对应的氨基酸不变。 参考资料 外部连结 突变 分子生物学 wikipedia.org
zh.wikipedia.org 0.0 0.0 0.0
13
Google DeepMind Machine Learning Method Predicts Pathogenic Effects of ...
Sep 19, 2023"What we are presenting today is our project called AlphaMissense," Pushmeet Kohli, VP of research in AI for science at Google DeepMind, said during a press briefing on Monday. ... Kohli and his colleagues used the AlphaMissense tool to tally likely pathogenic outcomes across the suite of missense mutations that might arise in more than 19,200 ...
www.genomeweb.com 0.0 0.0 0.0
14
Protein wntless homolog
A homozygous missense mutation in the WLS gene was identified in Zaki syndrome. References Further reading See also G protein-coupled receptors wikipedia.org
en.wikipedia.org 0.0 0.0 0.0
15
Lujan-Fryns综合症
原因 A missense mutation in the MED12 gene, located on the human X chromosome, has been established as the cause of LFS. The missense mutation in the MED12 gene, that causes LFS, is identified as p.N1007S. wikipedia.org
zh.wikipedia.org 0.0 0.0 0.0