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macrocyclic
macrocyclic, a. (mækrəʊˈsaɪklɪk) [f. macro- + cyclic a.] 1. Bot. Of a rust fungus: having a long life cycle.1926 Arthur & Kern in Mycologia XVIII. 90 The vegetative body is either long-cycle (macrocyclic), consisting of two unlike and discontinuous generations, or short-cycle (microcyclic), consisti...
Oxford English Dictionary
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Macrocyclic ligand
Macrocyclic effect
The macrocyclic effect is the high affinity of metal cations for macrocyclic ligands, compared to their acyclic analogues. Synthesis
In general, macrocyclic complexes are synthesized by combining macrocyclic ligands and metal ions.
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Macrocyclic stereocontrol
Macrocyclic stereocontrol refers to the directed outcome of a given intermolecular or intramolecular chemical reaction, generally an organic reaction, The degree to which a macrocyclic ring is either rigid or floppy depends significantly on the substitution of the ring and the overall size.
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microcyclic
microcyclic, a. Bot. (maɪkrəʊˈsaɪklɪk) [f. micro- 1 b + cyclic a.] Of a plant rust: having a short life cycle.1926 [see macrocyclic a. 1]. 1950 E. A. Bessey Morphol & Taxon. Fungi xii. 396 These last two are properly speaking microcyclic rusts. 1970 J. Webster Introd. Fungi 376 Some rusts have only ...
Oxford English Dictionary
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Macrocycle
Many metallocofactors are bound to macrocyclic ligands, which include porphyrins, corrins, and chlorins. Subdivisions
Cryptand
Rotaxane
Catenane
Molecular knot
Effective molarity
Macrocyclic stereocontrol
See also
Macrocyclic ligand
References
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macrolide
macrolide Pharm. (ˈmækrəlaɪd) [ad. Polish makrolid (Z. Katula 1958, in Postepy Hig. i Med. Dosiviadczalnej XII. 491): see macro- and lactide.] Any of a class of antibiotics containing macrocyclic lactone rings.1960 Biol. Abstr. XXXV. 4202/2 From the fermentation products of various strains of Strept...
Oxford English Dictionary
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Tetra-amido macrocyclic ligand
Tetra-amido macrocyclic ligands (TAMLs) constitute a class of macrocyclic ligands.
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2.2.2-Cryptand
prepared starting with the diacylation of the diamine-diether:
[CH2OCH2CH2NH2]2 + [CH2OCH2COCl]2 → [CH2OCH2CH2NHC(O)CH2]2 + 2 HCl
The resulting macrocyclic The resulting macrocyclic diamine tetraether reacts with a second equivalent of [CH2OCH2COCl]2 to produce the macrobicyclic diamide.
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Macrocyclic peptides useful as immunomodulators - Google Patents
US201562111388P 2015-02-03. US201562204689P 2015-08-13. PCT/US2015/060265 2015-11-12 Macrocyclic peptides useful as immunomodulators. Data provided by IFI CLAIMS Patent Services. The present disclosure provides compounds which are immunomodulators and thus are useful for the amelioration of various diseases, including cancer and infectious ...
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Gadopiclenol
Gadopiclenol is a paramagnetic macrocyclic non-ionic complex of gadolinium. This is half the dose of standard macrocyclic GBCAs, which have a recommended dose of 0.1 mmol/kg.
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Macrocyclic peptides useful as immunomodulators - Google Patents
US4522811A 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides. US4447224A 1982-09-20 1984-05-08 Infusaid Corporation Variable flow implantable infusion apparatus. US4487603A 1982-11-26 1984-12-11 Cordis Corporation Implantable microinfusion ...
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Dihydrosirohydrochlorin
Dihydrosirohydrochlorin is one of several naturally occurring tetrapyrrole macrocyclic metabolic intermediates in the biosynthesis of vitamin B12 (cobalamin The latter is the first macrocyclic intermediate common to haem, chlorophyll, sirohaem and vitamin B12.
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Quinolidomicin
Quinolidomicin A1 is a 60-membered macrocyclic compound isolated from Micromonospora sp. JY16. Biosynthesis
Like many macrocyclic polyketides, quinolidomicin A1 is biosynthesized by type-I polyketide synthases.
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CN102812037A - Macrocyclic Ghrelin Receptor ... - Google Patents
The present invention provides novel conformationalIy- defined macrocyclic compounds of formula (I) that have been demonstrated to be selective modulators of the ghrelin receptor (GRLN, growth hormone secretagogue receptor, GHS-R1a and subtypes, isoforms and/or variants thereof). Methods of synthesizing the novel compounds are also described herein.
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Sirohydrochlorin
Sirohydrochlorin is a tetrapyrrole macrocyclic metabolic intermediate in the biosynthesis of sirohaem, the iron-containing prosthetic group in sulfite The latter is the first macrocyclic intermediate common to haem, chlorophyll, sirohaem and vitamin B12.
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