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Macrocycle - Wikipedia
Macrocycles are often described as molecules and ions containing a ring of twelve or more atoms. Classical examples include the crown ethers, calixarenes, ... en.wikipedia.org
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Macrocyclics: Home
Macrocyclics, Inc., a manufacturer of customized chelating agents, is dedicated to leading-edge development of new chelation chemistry platforms. macrocyclics.com
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Macrocycles in Drug Discovery—Learning from the Past for the Future
We have analyzed FDA-approved macrocyclic drugs, clinical candidates, and the recent literature to understand how macrocycles are used in drug discovery. pmc.ncbi.nlm.nih.gov
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macrocyclic
macrocyclic, a. (mækrəʊˈsaɪklɪk) [f. macro- + cyclic a.] 1. Bot. Of a rust fungus: having a long life cycle.1926 Arthur & Kern in Mycologia XVIII. 90 The vegetative body is either long-cycle (macrocyclic), consisting of two unlike and discontinuous generations, or short-cycle (microcyclic), consisti... Oxford English Dictionary
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Macrocyclic peptides: the next wave of drug discovery - Merck.com
Learn more about the science behind macrocyclic peptides and their therapeutic potential for drug candidates. www.merck.com
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Macrocyclic peptides: Aiming for the perfect fit - C&EN
A macrocyclic peptide is any string of 12 amino acids or more that curls into ring structures, according to Christian Heinis, who develops therapeutics based ... cen.acs.org
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Macrocyclic ligand
Macrocyclic effect The macrocyclic effect is the high affinity of metal cations for macrocyclic ligands, compared to their acyclic analogues. Synthesis In general, macrocyclic complexes are synthesized by combining macrocyclic ligands and metal ions. wikipedia.org
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Macrocyclic Compound - an overview | ScienceDirect Topics
Macrocyclic compounds are defined as cyclic structures that can originate from modified unicyclic molecules or natural products, exhibiting significant ... www.sciencedirect.com
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Obstacles and innovations of macrocyclic drug development
Macrocycles are used to combat a range of diseases, including cancer, viral, fungal and bacterial infections, neurodegenerative and autoimmune diseases. www.drugtargetreview.com
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MACROCYCLIC Definition & Meaning - Merriam-Webster
The meaning of MACROCYCLIC is containing or being a chemical ring that consists usually of 15 or more atoms. How to use macrocyclic in a sentence. www.merriam-webster.com
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Macrocyclic β-arch peptides that mimic the structure and function of ...
Here we implement a diversity-oriented peptide macrocyclization approach towards miniature tau, or 'mini-tau', proteomimetics that can seed the aggregation of ... www.nature.com
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Macrocyclic stereocontrol
Macrocyclic stereocontrol refers to the directed outcome of a given intermolecular or intramolecular chemical reaction, generally an organic reaction, The degree to which a macrocyclic ring is either rigid or floppy depends significantly on the substitution of the ring and the overall size. wikipedia.org
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microcyclic
microcyclic, a. Bot. (maɪkrəʊˈsaɪklɪk) [f. micro- 1 b + cyclic a.] Of a plant rust: having a short life cycle.1926 [see macrocyclic a. 1]. 1950 E. A. Bessey Morphol & Taxon. Fungi xii. 396 These last two are properly speaking microcyclic rusts. 1970 J. Webster Introd. Fungi 376 Some rusts have only ... Oxford English Dictionary
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macrolide
macrolide Pharm. (ˈmækrəlaɪd) [ad. Polish makrolid (Z. Katula 1958, in Postepy Hig. i Med. Dosiviadczalnej XII. 491): see macro- and lactide.] Any of a class of antibiotics containing macrocyclic lactone rings.1960 Biol. Abstr. XXXV. 4202/2 From the fermentation products of various strains of Strept... Oxford English Dictionary
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Tetra-amido macrocyclic ligand
Tetra-amido macrocyclic ligands (TAMLs) constitute a class of macrocyclic ligands. wikipedia.org
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