macrolide Pharm.
(ˈmækrəlaɪd)
[ad. Polish makrolid (Z. Katula 1958, in Postepy Hig. i Med. Dosiviadczalnej XII. 491): see macro- and lactide.]
Any of a class of antibiotics containing macrocyclic lactone rings.
| 1960 Biol. Abstr. XXXV. 4202/2 From the fermentation products of various strains of Streptomyces there have been isolated several dozen antibiotics, whose common characteristic is a macrocyclic lactic ring. These antibiotics are called macrolides. 1967 [see erythromycin]. 1968 New Scientist 28 Mar. 678/2 Tylosin is a macrolide antibiotic, and organisms resistant to it are often cross-resistant to other macrolides, such as erythromycin, oleandomycin, and spiromycin. |