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hydroxamic
hydroxamic, a. Chem. (haɪdrɒkˈsæmɪk) [tr. G. hydroxamsäure hydroxamic acid (H. Lossen 1869, in Ann. d. Chem. u. Pharm. CL. 315), f. hydrox(ylamin hydroxylamine + am(id amide: see -ic.] hydroxamic acid: any of the acyl derivatives, R·CO· NHOH or (R·CO)2NHOH, of hydroxylamine (see quot. 1966).1875 Jrn...
Oxford English Dictionary
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Hydroxamic acid
A well-known reaction of hydroxamic acid esters is the Lossen rearrangement. Ligands derived from hydroxamic acid and thiohydroxamic acid also form strong complexes with lead(II).
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Acetohydroxamic acid
See also
Salicylhydroxamic acid
References
Orphan drugs
Hydroxamic acids
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Oxametacin
References
Tryptamines
Hydroxamic acids
Phenol ethers
Chloroarenes
Benzamides
Nonsteroidal anti-inflammatory drugs
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Aspergillic acid
They suggested that it is a cyclic hydroxamic acid related to pyridine. Because of this, aspergillic acid has been assigned the corresponding l-oxide or tautomeric pyridine hydroxamic acid structure show below.
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Ilomastat
Ilomastat is a member of the hydroxamic acid class of reversible metallopeptidase inhibitors. References
Hydroxamic acids
Matrix metalloproteinase inhibitors
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羟肟酸
羟肟酸,英文hydroxamic acid,是一类有机物,是羧酸分子中羧基二价氧被肟基取代的羧酸衍生物。
化学性质
羟肟酸存在几何异构体,因为其中的肟基具有不对称性。另外,羟肟酸也具有酸性,其中羟基氢与肟基氢都能产生氢离子。
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Givinostat
It is a hydroxamic acid used in the form of its hydrochloride. References
Further reading
Hydroxamic acids
Histone deacetylase inhibitors
Orphan drugs
Experimental drugs
Diethylamino compounds
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Ibuproxam
Ibuproxam is a nonsteroidal anti-inflammatory drug (NSAID).It is the hydroxamic acid of ibuprofen to which it is hydrolyzed in the blood. References
Hydroxamic acids
Anti-inflammatory agents
Benzene derivatives
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Abexinostat
References
Benzofuran-2-carboxamides
Hydroxamic acids
Histone deacetylase inhibitors
Antineoplastic drugs
Experimental cancer drugs
Benzamides
2-Phenoxyethanamines
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Pracinostat
Pracinostat (SB939) is an orally bioavailable, small-molecule histone deacetylase (HDAC) inhibitor based on hydroxamic acid with potential anti-tumor activity References
Histone deacetylase inhibitors
Benzimidazoles
Hydroxamic acids
Diethylamino compounds
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TAPI-1
References
TNF inhibitors
Hydroxamic acids
2-Naphthyl compounds
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Piroctone olamine
Piroctone olamine is the ethanolamine salt of the hydroxamic acid derivative piroctone was first synthesized in 1979 by Schwarzkopf-Henkel (Germany). References
Antifungals
Hydroxamic acids
Ethanolamines
2-Pyridones
Cosmetics chemicals
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Hadacidin
Hadacidin is the simplest known naturally occurring hydroxamic acid. Notes
Alpha-Amino acids
Amino acid derivatives
Hydroxamic acids
Formamides
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