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glyoxalase

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glyoxalase
glyoxalase Biochem. (glaɪˈɒksəleɪz, -s) [f. prec. + -ase.] Either of two enzymes which together convert methylglyoxal to lactic acid in the presence of glutathione; orig. considered a single enzyme.1913 Dakin & Dudley in Jrnl. Biol. Chem. XIV. 423 The catalyst..effects the rapid conversion of methyl... Oxford English Dictionary
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Glyoxalase system
Overview of Glyoxalase Pathway Glyoxalase I (GLO1), glyoxalase II (GLO2), and reduced glutathione (GSH). In bacteria, there is an additional enzyme that functions if there is no GSH, it is called the third glyoxalase protein, glyoxalase 3 (GLO3). wikipedia.org
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Lactoylglutathione lyase
The glyoaxalase system consists of two enzymes, glyoxalase I and glyoxalase II. Glyoxalase I. wikipedia.org
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Hydroxyacylglutathione hydrolase
It is commonly known as glyoxalase II. It participates in pyruvate metabolism. References EC 3.1.2 Enzymes of known structure wikipedia.org
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methyl
methyl Chem. (ˈmɛθɪl) Formerly also methule, -yle. [a. F. méthyle, G. methyl, a back-formation from F. méthylène, G. methylen, methylene. The G. methyl occurs in papers by Regnault in Ann. der Pharmacie XXXIII. 328 and XXXIV. 28 (1840). The back-formation was suggested by the fact that -yl (which Be... Oxford English Dictionary
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GLOD4
Glyoxalase domain-containing protein 4 is an enzyme that in humans is encoded by the GLOD4 gene. References Further reading wikipedia.org
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ophthalmic
ophthalmic, a. and n. (ɒfˈθælmɪk) [ad. L. ophthalmic-us (in Martial as n. ‘an oculist’), a. Gr. ὀϕθαλµικ-ός of or pertaining to the eye, f. ὀϕθαλµός eye: see -ic.] A. adj. 1. Pertaining or relating to the eye, ocular; connected with the eye, as a nerve, artery, etc.; affecting the eye, as a disease.... Oxford English Dictionary
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Methylglyoxal
One of these is the glyoxalase system. Methylglyoxal is detoxified by glutathione. This thioester is hydrolyzed to -lactate by glyoxalase II. wikipedia.org
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iodo-
iodo- (ˌaɪədəʊ, aɪˌəʊdəʊ) used as combining form of mod.L. iodum iodine (chiefly before a consonant): a. to form names of iodine compounds and substitution products resulting from the action of iodine on other bodies specified, e.g. ˌiodo-ˈbenzene, C6H5I1, formed from benzene by substitution of one ... Oxford English Dictionary
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Glutathione
This detoxification reaction is carried out by the glyoxalase system. Glyoxalase II (EC 3.1.2.6) catalyzes the hydrolysis of S-D-lactoylglutathione to glutathione and D-lactic acid. wikipedia.org
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Hemithioacetal
Hemithioacetals in nature Glyoxalase I, which is part of the glyoxalase system present in the cytosol, catalyzes the conversion of α-oxoaldehyde (RC(O) The spontaneous reaction forms methylglyoxal-glutathione hemithioacetal and human glyoxalase I. wikipedia.org
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Fosfomycin
Three related fosfomycin resistance enzymes (named FosA, FosB, and FosX) are members of the glyoxalase superfamily. wikipedia.org
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Triosephosphate isomerase
Methylglyoxal is a toxin and, if formed, is removed through the glyoxalase system. wikipedia.org
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Metallo-beta-lactamase protein fold
These proteins include thiolesterases, members of the glyoxalase II family, that catalyse the hydrolysis of S-D-lactoyl-glutathione to form glutathione wikipedia.org
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Advanced glycation end-product
See also Glycosylation Glyoxalase system Methylglyoxal Raw foodism N(6)-Carboxymethyllysine Lipofuscin References Biomolecules Post-translational modification wikipedia.org
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