trifluoperazine Pharm.
(ˌtraɪfluːəʊˈpɛrəziːn)
[f. tri- 5 + fluo- + piperazine.]
A phenothiazine derivative used as a tranquillizer and anti-emetic (usu. administered as the hydrochloride); 10-[3-(4-methylpiperazin-1-yl)propyl]-2-trifluoromethylphenothiazine, C21H24F3N3S.
| 1958 Amer. Jrnl. Psychiatry CXIV. 747 (heading) Triflupromazine and trifluoperazine: two new tranquilizers. Ibid. 747/2 The chlorine atom of the phenothiazine nucleus has been replaced by carbon trifluoride... This differentiates..trifluoperazine from prochlorperazine. 1965 [see Stelazine]. 1977 Lancet 15 Oct. 816/2 A 65-year-old woman had been taking ‘Parstelin’ tablets (tranylcypromine 10 mg, trifluoperazine 1 mg), one three times daily for a depressive illness for 4 years. 1984 Brit. Med. Jrnl. 8 Sept. 612/1 He was diagnosed as having an anxiety neurosis and was prescribed trifluoperazine together with orphenadrine. |