primidone Pharm.
(ˈprɪmɪdəʊn)
[f. pyrimidine + -dione.]
A white, crystalline pyrimidine derivative, C12H14N2O2, which is an anticonvulsant used esp. to treat grand mal and psychomotor epilepsy. Cf. Mysoline.
| 1953 Brit. Med. Jrnl. 5 Sept. 540/1 The introduction of primidone (‘mysoline’; 5-phenyl-5-ethylhexahydropyrimidine-4:6-dione) as an anticonvulsant drug some two years ago. 1958 [see Mysoline]. 1961 Lancet 9 Sept. 569/1 He was treated with primidone..and benzhexol hydrochloride..with striking reduction in the frequency of the seizures. Ibid. 569/2 He was discharged on primidone therapy. 1974 M. C. Gerald Pharmacol. xi. 214 Among the safest and most effective drugs are..primidone (Mysoline) and diphenylhydantoin for psychomotor seizures. |