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pyrimidine

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pyrimidine
pyrimidine Chem. (pɪˈrɪmɪdiːn, paɪər-) Also † -in. [ad. G. pyrimidin (A. Pinner 1885, in Ber. d. Deut. Chem. Ges. XVIII. 760) f. pyridin pyridine with inserted -im (f. imid imide).] A colourless, crystalline basic solid, CH:N·CH:N·CH:CH ; any substituted derivative containing this ring structure, sp... Oxford English Dictionary
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Pyrimidine phosphorylase
Pyrimidine phosphorylase may refer to: Thymidine phosphorylase Uridine phosphorylase wikipedia.org
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Pyrimidine dimer
Pyrimidine dimers are the primary cause of melanomas in humans. A 6–4 photoproduct (6–4 pyrimidine–pyrimidone or 6–4 pyrimidine–pyrimidinone) is an alternate dimer consisting of a single covalent bond between the carbon wikipedia.org
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Pyrimidine analogue
Pyrimidine analogues are antimetabolites which mimic the structure of metabolic pyrimidines. synthase Floxuridine (FUDR) 6-azauracil (6-AU) Nucleoside analogues Cytarabine (Cytosine arabinoside) Gemcitabine Nucleotide analogues Medical uses Pyrimidine wikipedia.org
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Deoxyribonuclease (pyrimidine dimer)
Deoxyribonuclease (pyrimidine dimer) (, endodeoxyribonuclease (pyrimidine dimer), bacteriophage T4 endodeoxyribonuclease V, T4 endonuclease V) is an enzyme This enzyme catalyses the following chemical reaction: Endonucleolytic cleavage near pyrimidine dimers to products with 5'-phosphate This enzyme acts wikipedia.org
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How can a three-base codon evolve from a two-base codon? Inspired by this question among others. It's widely suggested that the current 3-base codon system of encoding protein sequences in DNA evolved from an earlier...
Its also likely that between 2 and 3 base codes a 2 base pyrimidine/purine system was used. Today the third base can often be switched for its pyrimidine/purine pair without changing the resulting amino acid.
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Pyrimidine oxygenase
Pyrimidine oxygenase (, RutA) is an enzyme with systematic name ''). wikipedia.org
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Pyrimidine-nucleoside phosphorylase
In enzymology, a pyrimidine-nucleoside phosphorylase () is an enzyme that catalyzes the chemical reaction a pyrimidine nucleoside + phosphate a pyrimidine This enzyme participates in pyrimidine metabolism. wikipedia.org
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Pyrimidine-containing tri-substituted imidazole compound and ...
Disclosed are a pyrimidine-containing tri-substituted imidazole compound having the structure shown in formula (I) and an application thereof. The compound can effectively inhibit EGFR C797S mutations including EGFR ex19del/T790M/C797S and L858R/T790M/C797S, at the same time, it also has higher inhibitory activity against single point mutations L858R, ex19del and double-point mutations such as ...
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Cardiogenol C A cell-permeable pyrimidine compound that potently ...
A cell-permeable pyrimidine compound that potently induces the differentiation of ESCs (embryonic stem cells) into cardiomyocytes (EC 50 = 100 nM) without significant cytotoxic effect even at concentrations as high as 25 µM. The induction of cardiomyogenesis by Cardiogenol C is much more efficient than that achieved by EBs (embryoid bodies) formation and DMSO treatment.
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LOINC 79668-0 Purine and Pyrimidine panel - Cerebral spinal fluid
R/O/C. Cardinality. Example UCUM Units. 79668-0. Purine and Pyrimidine panel - Cerebral spinal fluid. Indent. 75124-8. Deoxyadenosine [Moles/volume] in Cerebral spinal fluid.
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Pyrimidine metabolism
Pyrimidine biosynthesis occurs both in the body and through organic synthesis. De novo biosynthesis of pyrimidine De Novo biosynthesis of a pyrimidine is catalyzed by three gene products CAD, DHODH and UMPS. wikipedia.org
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TW201245190A - Bicyclic pyrimidine derivative - Google Patents
The object of the present invention is to provide a compound or a physiologically acceptable salt thereof which has a MGAT inhibitory effect and is useful as a medicament, and a pharmaceutical composition comprising the same. A bicyclic pyrimidine compound of formula (I): wherein R1 is optionally substituted lower alkyl, etc., R2 is hydrogen atom, etc., R3 is hydrogen atom, etc., R4 and R5 are ...
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Pyrimidine-5'-nucleotide nucleosidase
In enzymology, a pyrimidine-5'-nucleotide nucleosidase () is an enzyme that catalyzes the chemical reaction a pyrimidine 5'-nucleotide + H2O D-ribose -phosphate and pyrimidine base. wikipedia.org
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Uses of egfr/her2 inhibitor combined with pyrimidine-type anti ...
The present invention relates to uses of an EGFR/HER2 inhibitor combined with a pyrimidine-type anti-metabolic drug, and specifically, to uses of an EGFR/HER2 receptor tyrosine kinase inhibitor combined with pyrimidine-type anti-metabolic drug in the preparation of drugs for treating cancers.
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