uracil

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uracil
uracil Biochem. (ˈjʊərəsɪl) [a. G. uracil (R. Behrend 1885, in Ann. d. Chemie CCXXIX. 11), of unknown origin (perh. f. Eng. urea + G. ac-etsäure acetic acid + -il).] A pyrimidine base, C4H4N2O2, which is a constituent of RNA.1890 Roscoe & Schorlemmer Treat. Chem. (ed. 2) III. 387 Behrend has succeed... Oxford English Dictionary
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Uracil phosphoribosyltransferase
Uracil phosphoribosyltransferase is an enzyme which creates UMP from uracil and phosphoribosylpyrophosphate. wikipedia.org
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Uracil glycol
Uracil glycol is a major oxidation product of cytosine in DNA. wikipedia.org
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Uracil dehydrogenase
Uracil dehydrogenase (, uracil oxidase) is an enzyme with systematic name uracil:(acceptor) oxidoreductase. This enzyme catalyses the following chemical reaction uracil + acceptor barbiturate + reduced acceptor Also oxidizes thymine. wikipedia.org
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Uracil-DNA glycosylase
Uracil-DNA glycosylase (also known as UNG or UDG) is an enzyme. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosidic bond wikipedia.org
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Standard letter for 5-methylcytosine I'm working on a piece of software that computes melting temperatures for nucleic acid duplexes, and I'm about to add support for 5-methylcytosine as a nucleotide base. At the mome...
Well, don't use **M** or **B** , those are already taken ( **C** or **A** , and **not A** , respectively). You can see the full list here: < (The enWiki article on Nucleobases lists a few others but I would ignore those as 1. D is present in both and 2. they are rare and inapplicable) 5-methylcytosi...
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Tegafur/uracil
Mechanism of action Excess uracil competes with 5-FU for DPD, thus inhibiting 5-FU catabolism. The uracil causes higher amounts of 5-FU to stay inside the cells and kill them. Tegafur is a type of antimetabolite. wikipedia.org
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Does DNA have 5 nitrogenous bases? Does DNA have 5 nitrogenous bases? I believe they are 5 because Uracil is not the same thing as Guanine, because, first of all, uracil "replaces" thymine, not guanine. And second, ur...
It's a bit more complicated than that. This wiki entry on nucleotides should help clarify things: Nucleotide Diagram of chemical structure of bases, nucleosides, nucleotides, etc I'm not sure what you mean by "...a range of functions..."
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Uracil/thymine dehydrogenase
Uracil/thymine dehydrogenase (, uracil oxidase, uracil-thymine oxidase, uracil dehydrogenase) is an enzyme with systematic name uracil:acceptor oxidoreductase + reduced acceptor Uracil/thymine dehydrogenase forms part of the oxidative pyrimidine-degrading pathway in some microorganisms. wikipedia.org
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What is the purpose of DNA? My _very_ basic understanding is DNA gets transcribed into RNA by effectively replacing thymine with uracil, then RNA is translated to make proteins. Looking at it from an engineering persp...
Imagine you want to produce a widget. You have thousands of worker, but only one blueprint. Each worker needs the blueprint to build a widget (they're really forgetful and can't build from memory). So only one worker at a time can build your widgets. What you would do is to create copies of your blu...
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TRNA (uracil-5-)-methyltransferase
The systematic name of this enzyme class is S-adenosyl-L-methionine:tRNA (uracil-5-)-methyltransferase. Other names in common use include ribothymidyl synthase, transfer RNA uracil 5-methyltransferase, transfer RNA uracil methylase, tRNA uracil 5-methyltransferase wikipedia.org
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Can a dNTP be built into a RNA strand? DNA consists of deoxyribonucleotides, RNA consists of ribonucleotides. They differ mainly (apart from the uracil / thymine difference) in the sugar part, the deoxyribose and the ...
This is rather easy to do if you synthesize oligonucleotides chemically and not enzymatically. This is typically done using phosphoramidite chemistry, and it allows for the synthesis of chimeric RNA/DNA oligos. You can even incorporate modified nucleosides like 2'-O-Me or LNA. This is typically done...
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Uracil-5-carboxylate decarboxylase
The enzyme uracil-5-carboxylate decarboxylase () catalyzes the chemical reaction uracil 5-carboxylate uracil + CO2 This enzyme belongs to the family The systematic name of this enzyme class is uracil-5-carboxylate carboxy-lyase (uracil-forming). wikipedia.org
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5-amino-6-(5-phosphoribosylamino)uracil reductase
)uracil + NADP+ 5-amino-6-(5-phosphoribosylamino)uracil + NADPH + H+ Thus, the two substrates of this enzyme are 5-amino-6-(5-phosphoribitylamino)uracil and NADP+, whereas its 3 products are 5-amino-6-(5-phosphoribosylamino)uracil, NADPH, and H+. wikipedia.org
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