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tyrosinase
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tyrosinase
tyrosinase Biochem. (ˈtaɪərəs-, taɪˈrɒsɪneɪz) [a. F. tyrosinase (G. Bertrand 1896, in Compt. Rend. CXXII. 1216): see tyrosine and -ase.] A copper-containing oxygenase found in many plants and animals which catalyses the formation of quinones from phenols and polyphenols (e.g. melanin from tyrosine) ...
Oxford English Dictionary
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Tyrosinase
As opposed to fungal tyrosinase, human tyrosinase is a membrane-bound glycoprotein and has 13% carbohydrate content. one ancestral tyrosinase gene.
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Dihydromorin
Dihydromorin is an inhibitor of tyrosinase.
See also
Norartocarpetin, the corresponding flavone
References
Flavanonols
Resorcinols
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tyrosine
tyrosine Chem. (ˈtaɪərəʊsiːn) Also † -in. [irreg. f. Gr. τῡρός cheese + -in1.] An amino-acid that is the precursor of several hormones, including adrenalin; 3-(p-hydroxyphenyl)alanine. Also attrib.1857 Miller Elem. Chem. III. 627 Tyrosine..was obtained by Liebig from the products of the fusion of we...
Oxford English Dictionary
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Dopachrome tautomerase
See also
Tyrosinase-related protein 1 (TYRP1)
Dopachrome, a cyclization product of L-DOPA and is an intermediate in the biosynthesis of melanin.
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Tyrosine phenol-lyase
Other names in common use include beta-tyrosinase, and L-tyrosine phenol-lyase (deaminating).
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which of the following is a characteristic of melanin
Tyrosinase is a copper-containing enzyme present in plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine
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Arbutin
Applied topically, it inhibits tyrosinase and thus prevents the formation of melanin. Arbutin is therefore used as a skin-lightening agent. In vitro studies of human melanocytes exposed to arbutin at concentrations below 300 μg/mL reported decreased tyrosinase activity and melanin content with
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Rhododendrol
Rhododendrol exerts melanocyte cytotoxicity via a tyrosinase-dependent mechanism. It is now well established that rhododendrol is a potent tyrosinase inhibitor.
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熊果素
熊果素(Arbutin,C12H16O7),亦作熊果苷,是一种由杜鹃花科植物熊果叶中萃取出的成份,在梨、小麦等植物中也有发现,因为能抑制酪氨酸酶(tyrosinase)的活性,进而阻碍黑色素的形成,对美白颇具功效,因而被用于化粧及保养品中。
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L-dopachrome isomerase
Other names in common use include dopachrome tautomerase, tyrosinase-related protein 2, TRP-1, TRP2, TRP-2, tyrosinase-related protein-2, dopachrome Delta7
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Oculocutaneous albinism type I
Genetics
The tyrosinase (TYR) gene is located on chromosome 11q14. OCA1A results in complete loss of tyrosinase enzyme activity.
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Poly-gamma-glutamate
Poly-γ-glutamate inhibits tyrosinase and melanogenesis in vitro.
References
Organic polymers
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4-Butylresorcinol
Hyperpigmentation is believed to be related to the enzyme tyrosinase which produces melanin. Among several chemicals known to inhibit tyrosinase production, such as hydroquinone, arbutin, and kojic acid, 4-butylresorcinol has been found to be the
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Glabrene
It has also been found to act as a tyrosinase inhibitor (IC50 = 3.5 μM) and to inhibit the formation of melanin in melanocytes, and for these reasons,
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