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tuberculin
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tuberculin
tuberculin Med. (tjuːˈbɜːkjʊlɪn) Also erron. -ine. [f. L. tūberculum tubercle + -in1.] a. A liquid prepared from cultures of tubercle-bacillus, originally by Dr. Koch of Berlin in 1890, or any one of various later modifications of this, used by hypodermic injection as a remedy, or (now esp.) as a te...
Oxford English Dictionary
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Tuberculin
Tuberculin was discovered in 1890 by Robert Koch. His observations led to the development of the tuberculin skin test.
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Tuberculinic acid
From the crushed bacilli, specifically the protein tuberculin, he isolated two toxic substances, namely a basic compound which he called tuberculosamine Ruppel also found that his new compound was the most toxic component of the bacillus, 2.5 to 6 times more potent than tuberculin, the proteinaceous toxin
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leprolin
leprolin Med. (ˈlɛprəʊlɪn) [f. leprosy + -lin, after tuberculin.] = lepromin.1904 E. R. Rost in Indian Med. Gaz. XXXIX. 168/2 The next thing that was attempted was the manufacture of a leprolin on the lines of the manufacture of tuberculin. 1934 Brit. Med. Jrnl. 21 Apr. 703/2 The typical reaction to...
Oxford English Dictionary
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Royal Commission on Tuberculosis
In 1890 the German physician and microbiologist Robert Koch developed tuberculin, a purified protein derivative of the bacteria. In 1891 The Veterinary College at Dorpat produced seminal research using the Tuberculin test on 1,000 cattle.
and by 1891 the British Medical Journal was
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Koch
Koch (kɒx, kɒk) The name of Robert Koch (1843–1910), Ger. bacteriologist, used in the possessive (less commonly attrib.) to designate certain things related to his work on tuberculosis, as Koch's bacillus, Mycobacterium tuberculosis, which causes tuberculosis in man, and was first isolated by Koch; ...
Oxford English Dictionary
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Mantoux test
Seibert identified the active agent in tuberculin as a protein. Procedure
In the Mantoux test, a standard dose of 5 tuberculin units (TU - 0.1 ml), according to the CDC, or 2 TU of Statens Serum Institute (SSI) tuberculin
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Latent tuberculosis
skin testing
The tuberculin skin test (TST) in its first iteration, the Mantoux Test, was developed in 1908. conversion
Tuberculin conversion is said to occur if a patient who has previously had a negative tuberculin skin test develops a positive tuberculin skin
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T-SPOT.TB
While the tuberculin skin test uses purified protein derivative, a heterogeneous mixture of more than two hundred different mycobacterial peptides, the Based on those test principles, it is thought that the T-SPOT.TB is more specific than the tuberculin skin test.
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Tine test
Procedure
This test uses a small "button" that has four to six short needles coated with TB antigens (tuberculin), either an old tuberculin or a PPD-tuberculin PPD
Tuberculin is a glycerol extract of the tubercle bacillus.
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Tuberculosis diagnosis
It may also include a tuberculin skin test, other scans and X-rays, surgical biopsy. Tuberculin skin test
Two tests are available: the Mantoux and Heaf tests.
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Fernandez reaction
In terms of mechanism of action and appearance, the reaction is similar to the tuberculin reaction of a positive Mantoux test for tuberculosis.
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Francis M. Pottenger Sr.
Pottenger advocated the use of tuberculin which he believed would create a hostile environment for tuberculosis. Selected publications
Culture Products in the Treatment of Tuberculosis (1902)
The Diagnosis and Treatment of Pulmonary Tuberculosis (1908)
Tuberculin
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Florence B. Seibert
She is best known for identifying the active agent in the antigen tuberculin as a protein, and subsequently for isolating a pure form of tuberculin, purified Her first publication on the purification of tuberculin appeared in 1934.
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Lichen scrofulosorum
The eruption is usually associated with a strongly positive tuberculin reaction.
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