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transferrin

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Biochemistry, Transferrin - StatPearls - NCBI Bookshelf
Transferrin is a blood plasma glycoprotein that plays a central role in iron metabolism by delivering ferric ions to various tissues, such as the liver, spleen, and bone marrow . Transferrin has a high affinity for ferric iron; therefore, there is little free iron in the body as transferrin binds almost all plasma iron. www.ncbi.nlm.nih.gov
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Transferrin - Wikipedia
Transferrins are glycoproteins found in vertebrates which bind and consequently mediate the transport of iron (Fe) through blood plasma. en.wikipedia.org
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Transferrin - University of Rochester Medical Center
Your liver makes transferrin. When your body's stores of iron run low, your liver makes more transferrin to get more iron into your blood. Iron plays many ... www.urmc.rochester.edu
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transferrin
transferrin Biochem. (trɑːnsˈfɛrɪn, træns-, -nz-) [f. trans- + L. ferr-um iron + -in1.] Any of several beta globulins found in blood serum which bind and transport iron; = siderophilin s.v. sidero-1 2.1947 Holmberg & Laurell in Acta Chemica Scandinavica I. 950 We suggest that the new metal-combining... Oxford English Dictionary
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Transferrin - an overview | ScienceDirect Topics
Transferrin is defined as a carrier protein that transports iron into animal cells, which is essential for optimal cell growth and expansion. www.sciencedirect.com
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7018 - Gene ResultTF transferrin [ (human)] - NCBI
Studies indicate that several genes have been linked to iron homeostasis, including transferrin (TF), iron regulatory protein 1 (ACO1) and ... www.ncbi.nlm.nih.gov
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TF - Serotransferrin - Homo sapiens (Human) | UniProtKB | UniProt
Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, ... www.uniprot.org
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Transferrin receptors | Experimental & Molecular Medicine - Nature
TfR is one of the key proteins involved in cellular iron uptake. TfR-mediated endocytosis of transferrin-bound iron is the major pathway for iron acquisition ... www.nature.com
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Transferrin: the iron transporter takes control - ASH Publications
Transferrin, the primary iron transport protein in the bloodstream, binds iron released by enterocytes via ferroportin. ashpublications.org
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Transferrin in Cell Culture - Sigma-Aldrich
Transferrin is the physiologically appropriate method for providing iron to cells in culture. The delivery of iron using transferrin has historically been part ... www.sigmaaldrich.com
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Transferrin and Iron-binding Capacity (TIBC, UIBC) Test - Testing.com
Test Quick Guide. Transferrin is the main protein in the blood that binds to iron and transports it throughout the body. A transferrin test ... www.testing.com
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Transferrin saturation
A low transferrin saturation is a common indicator of iron deficiency anemia whereas a high transferrin saturation may indicate iron overload or hemochromatosis Transferrin saturation is also called transferrin saturation index (TSI) or transferrin saturation percentage (TS%) Interpretation Studies also reveal wikipedia.org
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Transferrin receptor
Transferrin receptor (TfR) is a carrier protein for transferrin. Earlier two transferrin receptors in humans, transferrin receptor 1 and transferrin receptor 2 had been characterized and until recently cellular iron wikipedia.org
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Transferrin receptor 1
TfR1 is required for iron import from transferrin into cells by endocytosis. Each monomer binds one holo-transferrin molecule creating an iron-Tf-TfR complex which enters the cell by endocytosis. wikipedia.org
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Transferrin receptor 2
This protein is involved in the uptake of transferrin-bound iron into cells by endocytosis, although its role is minor compared to transferrin receptor See also Transferrin receptor 1 Transferrin References Further reading External links GeneReviews/NIH/NCBI/UW entry on TFR2-Related or Type 3 Hereditary wikipedia.org
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