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tosyl
tosyl Chem. (ˈtɒsɪl) [a. G. tosyl (Hess & Pfleger 1933, in Ann. d. Chemie DVII. 48), f. toluolsulfonyl: see toluol (s.v. tolu-), sulphonyl.] The para isomer of the univalent radical toluenesulphonyl, H3C·C6H4·SO2—.1938 Jrnl. Amer. Chem. Soc. LX. 398/1 The unimolar tosylation of α- and β-methyl-d-glu...
Oxford English Dictionary
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Tosyl group
In organic chemistry, a toluenesulfonyl group (tosyl group, abbreviated Ts or Tos) is a univalent functional group with the chemical formula . Amine protection – tosyl (Ts)
Tosyl (Ts) group is commonly used as a protecting group for amines in organic synthesis.
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Tosyl azide
Tosyl azide is a reagent used in organic synthesis.
Uses
Tosyl azide is used for the introduction of azide and diazo functional groups. Preparation
Tosyl azide can be prepared by the reaction of tosyl chloride with sodium azide in aqueous acetone.
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Tosyl phenylalanyl chloromethyl ketone
Tosyl phenylalanyl chloromethyl ketone (TPCK) is a protease inhibitor. Its structural formula is 1-chloro-3-tosylamido-4-phenyl-2-butanone. References
Protease inhibitors
Sulfonamides
p-Tosyl compounds
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Brosyl group
See also
Tosyl group
Tosylic acid
Triflic acid
Sulfonyl group
Sulfonyl groups
Functional groups
References
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Tolazamide
References
External links
Potassium channel blockers
Benzenesulfonylureas
Azepanes
p-Tosyl compounds
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Aporphine
Then, 6-Tosyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-1-yl-pyridine-2-sulfonate is reacted to 6-Tosyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin This 6-Tosyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-1-yl Trifluoromethanesulfonate is then further reduced by palladium acetate, leading to 6-Tosyl
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Tosylhydrazone
A tosylhydrazone in organic chemistry is a functional group with the general structure RR'C=N-NH-Ts where Ts is a tosyl group. References
Functional groups
Hydrazones
p-Tosyl compounds
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Sulfonyl group
Example
|-
|Tosyl
|p-toluenesulfonyl
|Ts
|Tosyl chloride (p-toluenesulfonyl chloride)CH3C6H4SO2Cl
|-
|Brosyl
|p-bromobenzenesulfonyl
|Bs
|
|-
|Nosyl
|o
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4-Toluenesulfonyl chloride
The preparation of tosyl esters and amides are conducted in the presence of a base, which absorbs hydrogen chloride. References
Reagents for organic chemistry
Sulfonyl halides
p-Tosyl compounds
Foul-smelling chemicals
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P-Toluenesulfonic acid
The CH3C6H4SO2 group is known as the tosyl group and is often abbreviated as Ts or Tos. Most often, TsOH refers to the monohydrate, TsOH.H2O. See also
Tosyl
Collidinium p-toluenesulfonate
References
Benzenesulfonic acids
Reagents for organic chemistry
Acid catalysts
Sulfonic acids
P-Tosyl compounds
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Glibornuride
References
Potassium channel blockers
Secondary alcohols
1-(Benzenesulfonyl)-3-cyclohexylureas
p-Tosyl compounds
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Morpheridine
Thus, alkylation of benzyl cyanide (1) with the tosyl analog of the bischloroethylamine (2) leads to the substituted piperidine (3). Treatment of this last with sulfuric acid in ethanol serves both to esterify the acid and to remove the tosyl group to yield the secondary amine (5).
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Hurd–Mori 1,2,3-thiadiazole synthesis
thiadiazole synthesis is a name reaction in organic chemistry that allows for the generation of 1,2,3-thiadiazoles through the reaction of N-acylated or tosyl
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Diazaborine B
References
Organoboron compounds
Sulfonamides
P-Tosyl compounds
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