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smad
smad, v. Sc. rare. [Cf. LG. smaddern (G. dial. schmaddern) to befoul, f. smadder (schmadder) mud, filth.] trans. To cover with dirt or grime; to stain, discolour. Jamieson (1808) also gives Smad ‘a stain of any kind’.c 1450 Holland Howlat 825 The barde, smaddit lyke a smaik smorit in a smedy, Ran fa...
Oxford English Dictionary
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SMAD
metal atom dispersion, a method of producing nanoparticles
SMAD (protein), proteins involved in cell signaling
I-SMAD, inhibitory SMAD proteins
R-SMAD , receptor regulated SMAD proteins
Smad, Syria, a village in southern Syria
wikipedia.org
en.wikipedia.org
SMAD (protein)
Sub-types
The R-Smads consist of Smad1, Smad2, Smad3, Smad5 and Smad8/9, and are involved in direct signaling from the TGF-B receptor. Despite evidence showing that Smad3 is more critical than Smad2 in TGF-B signaling, the rate of Smad3 mutations in cancer is lower than that of Smad2.
wikipedia.org
en.wikipedia.org
I-SMAD
This class includes SMAD6 and SMAD7. They compete with SMAD4 and consequently regulate the transcription of its gene products. See also
SMAD (protein)
R-SMAD
External links
SMAD (protein)
Transcription factors
wikipedia.org
en.wikipedia.org
R-SMAD
R-SMADS include SMAD2 and SMAD3 from the TGF-β/Activin/Nodal branch, and SMAD1, SMAD5 and SMAD8 from the BMP/GDP branch of TGF-β signaling. These proteins then typically bind to the common mediator Smad or co-SMAD SMAD4.
wikipedia.org
en.wikipedia.org
SMAD5-AS1
In molecular biology, SMAD5 antisense RNA 1 (non-protein coding), also known as SMAD5-AS1 or DAMS is a long non-coding RNA. It is antisense to, and nested within, the SMAD5 gene. In humans it is found on chromosome 5.
wikipedia.org
en.wikipedia.org
Silencing and Overexpressing SMAD Family Member 1
1 College of Animal Science and Technology, Northwest A&F University, Yangling 712100, Shaanxi; 2 National Beef Cattle Improvement Center, Yangling 712100, Shaanxi Received:2018-12-06 Accepted:2019-02-26 Online:2019-05-16 Published:2019-05-23 Contact: LinSen ZAN E-mail:zanlinsen@163.com
www.chinaagrisci.com
the year of the establishment and the naming of the domed (mdo smad ...
the year of the establishment and the naming of the domed (mdo smad)pacification commission of the yuan dynasty
open.oriprobe.com
open.oriprobe.com
Based on TGF-β1/Smad signaling pathway, to explore the effect of ...
Objective: To observe the clinical efficacy of Fuzheng Jiedu Sanjie Recipe in the treatment of primary liver cancer(PHC),and to explore its effects on cellular immunity and tumor
zxyxhen.whuhzzs.com
Question about cell signaling pathways (RTK, Jak-Stat, SMAD, etc) I am in an embryology course right now and we've just started covering cell-cell communication in development. We were talking about the roles of the v...
@Alexandria Jak/Stat are two families of proteins which mediate signals through phosphotyrosines. JAK is a tyrosine kinase which binds to cell receptors and STAT is dimerized by JAK action. JAK specificity seems to be your question. A specific JAK protein (e.g. JAK1 or JAK2..) may mediate for differ...
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TGF-β/SMAD 信号通路| Abcam中文官网
经证实,tgf-β 通路协调着许多细胞过程,包括细胞生长、分化、细胞迁移、侵袭和细胞外基质重塑。该通路及其组分在多种肿瘤中呈失调状态。 在正常细胞和早期肿瘤中,tgf-β 信号传导通过抑制细胞生长和细胞凋亡来抑制肿瘤形成。 但是,细胞可以捕获 tgf-β 及其下游效应因子的突变,从而对这些 ...
www.abcam.cn