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sickling

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sickling
▪ I. ˈsickling1 [f. sickle n.] 1. The action of cutting with a sickle. Also attrib.1598 Florio, Segatura, a sawing, a mowing, a sickling. 1765 Museum Rust. IV. 358 The adoption of our method of sickling. Ibid., The wages..on the sickling scheme. 2. Path. The adoption of a crescent shape by red blood... Oxford English Dictionary
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John Sickling
John Sickling was a priest and academic in the late fifteenth and early sixteenth centuries. wikipedia.org
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sicklemia
sicklemia Path. (sɪk(ə)lˈiːmɪə) [contraction of sickle (cell anæ)mia.] Sickle cell anæmia or the sickle cell trait. Hence sicklˈemic a.1932 Amer. Jrnl. Med. Sic. CLXXXIII. 386 The term sicklemia has been suggested instead of sickle-cell anemia because a grave anemia is not constantly found in these ... Oxford English Dictionary
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Sickle cell trait
This is because the sickling happens only at low oxygen concentrations. Fetal hemoglobin likely plays a role in the prevention of sickling. wikipedia.org
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Sickle Cell Anemia, a Molecular Disease
the protein portion of hemoglobin (which was confirmed in 1956 by Vernon Ingram), and that this change in molecular structure is responsible for the sickling differences in size, weight, or acid-base titration (despite the advanced instruments available at Caltech), Itano found that oxygen could inhibit the sickling wikipedia.org
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What would the RBCs of someone heterozygous for sickle cell anemia look like? Would half of the RBCs look normal, and the other half sickled? Or would all of the RBCs have slight deformation/sickling? Thanks!
Each cell has only 30-40% HbS, and so the polymer that causes the sickling doesn't usually occur.
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Sickle cell disease
In sickle cell disease, low oxygen tension promotes red blood cell sickling and repeated episodes of sickling damage the cell membrane and decrease the Sickling of the red blood cells, on a blood film, can be induced by the addition of sodium metabisulfite. wikipedia.org
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Cetiedil
Cetiedil is a vasodilator and an anti-sickling agent. wikipedia.org
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Cystamine
potential medicinal compound in the case of Huntington's disease, Alzheimer's disease, carbon tetrachloride liver damage, and inhibition of erythrocyte sickling wikipedia.org
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Vasa recta (kidney)
significance The slow blood flow in the straight arterioles makes them a likely location of thrombosis from thrombophilia, or tissue loss due to red blood cell sickling wikipedia.org
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Acute chest syndrome
Cause Acute chest syndrome is often precipitated by a lung infection, and the resulting inflammation and loss of oxygen saturation leads to further sickling of red cells, thus exacerbating pulmonary and systemic hypoxemia, sickling, and vaso-occlusion. wikipedia.org
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Sunday O. Fadulu
Fadulu's research used an extract of the African "chewing stick," which he discovered, reverses sickling of red blood cells. wikipedia.org
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Friskney Eaudyke
The settlement is centred on the northwest-to-southeast Eau Dyke Road, between Low Road at the north-west and the staggered junction with Sickling Lane wikipedia.org
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Autosplenectomy
Increased deoxygenation causes sickling of red blood cells, which adhere to the spleen wall and splenic macrophages causing ischemia. wikipedia.org
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Lael Chisholm
Haylock, Penguin Random House (illustrator) 2020 – The Hug Blanket, Chris Gurney, Scholastic New Zealand (illustrator) 2021 – Grandpa Versus Swing, Tania Sickling wikipedia.org
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