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pyruvate

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pyruvate
pyruvate Biochem. (paɪˈruːveɪt) [f. pyruvic a. + -ate4.] 1. A salt or ester, or the anion, of pyruvic acid; loosely, denoting either anions or the acid itself.1855 H. Watts tr. Gmelin's Hand-bk. Chem. IX. 419 The Pyruvates are prepared by saturating the dilute acid with the base. 1905 Jrnl. Chem. So... Oxford English Dictionary
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Pyruvate carboxylase
Regulation Pyruvate carboxylase is allosterically regulated by acetyl-CoA, Mg-ATP, and pyruvate. Normally, excess pyruvate is shunted into gluconeogenesis via conversion of pyruvate into oxaloacetate, but because of the enzyme deficiency, excess pyruvate wikipedia.org
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Pyruvate cycle increases aminoglycoside efficacy and provides ...
The emergence and ongoing spread of multidrug-resistant bacteria puts humans and other species at risk for potentially lethal infections. Thus, novel antibiotics or alternative approaches are needed to target drug-resistant bacteria, and metabolic modulation has been documented to improve antibiotic efficacy, but the relevant metabolic mechanisms require more studies.
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Pyruvate oxidation | Cellular respiration (article) | Khan Academy
In prokaryotes, it happens in the cytoplasm. Overall, pyruvate oxidation converts pyruvate—a three-carbon molecule—into acetyl CoA —a two-carbon molecule attached to Coenzyme A—producing an NADH and releasing one carbon dioxide molecule in the process. Acetyl CoA acts as fuel for the citric acid cycle in the next stage of cellular ...
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Methyl pyruvate
Methyl pyruvate is the organic compound with the formula CH3C(O)CO2CH3. This colorless liquid is the methyl ester of pyruvic acid. wikipedia.org
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Membrane Permeability to Pyruvate Pyruvate seems to pass easily through the outer membrane of the mitochondrion but has difficulty entering the inner membrane (and gets in by H+ symport). I have two questions: (1) wha...
Pyruvate is negatively charged and quite polar, which makes it unfavourable to diffuse directly through any membrane. Specifically, pyruvate uses voltage dependent anion channels.
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Pyruvate decarboxylase
Pyruvate decarboxylase starts this process by converting pyruvate into acetaldehyde and carbon dioxide. of pyruvate to acetyl-CoA. wikipedia.org
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Pyruvate oxidation - where did the hydrogen come from? ![enter image description here]( (source: resource12ubio at sites.google.com) As shown in the diagram above, NAD+ is reduced and becomes NADH by gaining two el...
The Pyruvate Dehydrogenase Complex facilitates the removal of CO2, and the addition of two hydrogen atoms to the overall reaction come from the FADH2/FAD
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Pyruvate kinase
pyruvate kinase. Mammals have two pyruvate kinase genes, PK-LR (which encodes for pyruvate kinase isozymes L and R) and PK-M (which encodes for pyruvate kinase isozyme wikipedia.org
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How to read this diagram? I have diagram of oxidative decarboxylation of pyruvate pathway. The pathway is between glycolisis and Krebs cycle. How to read this diagram? This excerpt from _Harper's Illustrated Biochem...
It acts upon $NAD^+$ according to following equation: $NAD^+ + FADH_2\rightarrow NADH+H^++FAD$ Same way you can write other reactions, e.g. by pyruvate dehydrogenase: $Pyruvate+TDP\rightarrow CO_2+TDP-Hydroxyethyl$
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Pyruvate dehydrogenase
Pyruvate dehydrogenase is an enzyme that catalyzes the reaction of pyruvate and a lipoamide to give the acetylated dihydrolipoamide and carbon dioxide. Pyruvate dehydrogenase is usually encountered as a component, referred to as E1, of the pyruvate dehydrogenase complex (PDC). wikipedia.org
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ATP utilized in Glycolysis vs. Gluconeogenesis In glycolysis, the conversion of glucose to pyruvate results in a net gain of 2 ATP molecules. In gluconeogenesis however, the conversion of pyruvate back to glucose requ...
This energy is not lost, it is dissipated as heat. And this must happen because of thermodynamics -- the direction of the reaction is simply determined by the difference of energy between substrates and products, and it must be positive for the reaction to happen spontaneously.
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Pyruvate synthase
In enzymology, a pyruvate synthase () is an enzyme that catalyzes the interconversion of pyruvate and acetyl-CoA. Other names in common use include: pyruvate oxidoreductase, pyruvate synthetase, pyruvate:ferredoxin oxidoreductase, pyruvic-ferredoxin oxidoreductase wikipedia.org
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LOINC 2907-4 Pyruvate [Mass/volume] in Cerebral spinal fluid
2907-4 Pyruvate [Mass/volume] in Cerebral spinal fluid Active Part Description. LP15693-2 Pyruvate Pyruvic acid (CH3COCOOH), an organic acid, is also a ketone and the simplest alpha-keto acid. The carboxylate (COOH) ion (anion) of pyruvic acid, CH3COCOO-, known as pyruvate, is a key intermediary in several metabolic pathways.
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Pyruvate oxidase
In enzymology, a pyruvate oxidase () is an enzyme that catalyzes the chemical reaction pyruvate + phosphate + O2 acetyl phosphate + CO2 + H2O2 The 3 Other names in common use include pyruvic oxidase, and phosphate-dependent pyruvate oxidase. This enzyme participates in pyruvate metabolism. wikipedia.org
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