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Pyruvate - an overview | ScienceDirect Topics
Pyruvate is defined as an alpha-keto acid that serves as a screening molecule for cancer diagnosis and is associated with elevated levels in cardiovascular diseases, brain abnormalities, and diabetes mellitus . AI generated definition based on: Microchemical Journal, 2019.
www.sciencedirect.com
www.sciencedirect.com
Pyruvic acid - Wikipedia
Pyruvic acid (CH3COCOOH) is the simplest of the alpha-keto acids, with a carboxylic acid and a ketone functional group. Pyruvate, the conjugate base, ...
en.wikipedia.org
en.wikipedia.org
Regulation of pyruvate metabolism and human disease - PMC
Pyruvate is a keystone molecule critical for numerous aspects of eukaryotic and human metabolism. Pyruvate is the end-product of glycolysis, is derived from ...
pmc.ncbi.nlm.nih.gov
pmc.ncbi.nlm.nih.gov
pyruvate
pyruvate Biochem. (paɪˈruːveɪt) [f. pyruvic a. + -ate4.] 1. A salt or ester, or the anion, of pyruvic acid; loosely, denoting either anions or the acid itself.1855 H. Watts tr. Gmelin's Hand-bk. Chem. IX. 419 The Pyruvates are prepared by saturating the dilute acid with the base. 1905 Jrnl. Chem. So...
Oxford English Dictionary
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Pyruvate - Uses, Side Effects, and More - WebMD
Pyruvate is a three-carbon acid that is naturally formed during glycolysis, the process in which the body breaks down sugar (glucose).
www.webmd.com
www.webmd.com
Pyruvate oxidation | Cellular respiration (article) - Khan Academy
pyruvate oxidation converts pyruvate—a three-carbon molecule—into acetyl ... CoA ... a two-carbon molecule attached to Coenzyme A—producing an ... NADH ... and ...
www.khanacademy.org
www.khanacademy.org
Pyruvate carboxylase
Regulation
Pyruvate carboxylase is allosterically regulated by acetyl-CoA, Mg-ATP, and pyruvate. Normally, excess pyruvate is shunted into gluconeogenesis via conversion of pyruvate into oxaloacetate, but because of the enzyme deficiency, excess pyruvate
wikipedia.org
en.wikipedia.org
Pyruvate | C3H3O3- | CID 107735 - PubChem
Pyruvate is a 2-oxo monocarboxylic acid anion that is the conjugate base of pyruvic acid, arising from deprotonation of the carboxy group.
pubchem.ncbi.nlm.nih.gov
pubchem.ncbi.nlm.nih.gov
Pyruvate - Bioblast
Pyruvate is formed in glycolysis from phosphoenolpyruvate. In the cytosol, pyruvate is a substrate of lactate dehydrogenase.
www.bioblast.at
www.bioblast.at
Pyruvate | Definition, Structure & Uses - Lesson - Study.com
Pyruvate is a key biomolecule in many metabolic pathways. It is most notable as the primary product of glycolysis.
study.com
study.com
5.6B: Breakdown of Pyruvate - Biology LibreTexts
Each pyruvate molecule loses a carboxylic group in the form of carbon dioxide. The remaining two carbons are then transferred to the enzyme CoA to produce ...
bio.libretexts.org
bio.libretexts.org
Pyruvate cycle increases aminoglycoside efficacy and provides ...
The emergence and ongoing spread of multidrug-resistant bacteria puts humans and other species at risk for potentially lethal infections. Thus, novel antibiotics or alternative approaches are needed to target drug-resistant bacteria, and metabolic modulation has been documented to improve antibiotic efficacy, but the relevant metabolic mechanisms require more studies.
www.ncbi.nlm.nih.gov
Methyl pyruvate
Methyl pyruvate is the organic compound with the formula CH3C(O)CO2CH3. This colorless liquid is the methyl ester of pyruvic acid.
wikipedia.org
en.wikipedia.org
Membrane Permeability to Pyruvate Pyruvate seems to pass easily through the outer membrane of the mitochondrion but has difficulty entering the inner membrane (and gets in by H+ symport). I have two questions: (1) wha...
Pyruvate is negatively charged and quite polar, which makes it unfavourable to diffuse directly through any membrane. Specifically, pyruvate uses voltage dependent anion channels.
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Pyruvate decarboxylase
Pyruvate decarboxylase starts this process by converting pyruvate into acetaldehyde and carbon dioxide. of pyruvate to acetyl-CoA.
wikipedia.org
en.wikipedia.org