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polysome
polysome Biol. (ˈpɒlɪsəʊm) [f. poly- + ribosome.] A cluster of ribosomes, held together by a strand of messenger RNA which each is translating; = polyribosome s.v. poly- 1.1962 J. R. Warner et al. in Science 28 Dec. 1399/2 We have been able to show that the site of hemoglobin synthesis in vivo is no...
Oxford English Dictionary
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Polysome
A polyribosome (or polysome or ergosome) is a group of ribosomes bound to an mRNA molecule like “beads” on a “thread”. Multiple ribosomes move along the coding region of mRNA, creating a polysome.
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Polysome (crystallography)
In crystallography, the term polysome is used to describe overall mineral structures which have structurally and compositionally different framework structures
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monosome
monosome Cytology. (ˈmɒnəsəʊm) [f. mono- + -some4.] 1. A chromosome in a diploid chromosome complement which lacks its homologous partner; a diploid individual having such a chromosome in its complement.1921 [see hexasome s.v. hexa-]. 1944 Genetics XXIX. 232, 16 monosomes and five trisomes were foun...
Oxford English Dictionary
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Polysome profiling
Polysome profiling is a technique in molecular biology that is used to study the association of mRNAs with ribosomes. in the 40S fraction, then nearly disappears from the 60S fraction (the separations on these gradients are not absolute), then reappears in the 80S and polysome
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ergosome
ergosome Biochem. (ˈɜːgəsəʊm) [f. Gr. ἔργον work + ribosome.] (See quots.)1963 F. O. Wettstein et al. in Nature 2 Feb. 434/2 In this article we have described a novel ribosomal particle which appears to be the functional unit of protein synthesis and which we therefore propose to call ‘ergosome’. 19...
Oxford English Dictionary
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Translatomics
Polysome profiling
Polysome profiling is a technique used to characterize the degree of translation of one or more mRNAs. In polysome profiling, a sucrose gradient is used to separate molecular complexes in a cell lysate based on size.
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pleiotypic
pleiotypic, a. Biol. (plaɪəʊˈtɪpɪk) [f. pleio- + type n.1 + -ic.] Pertaining to the process whereby a single stimulus can elicit multiple unrelated responses from a living cell.1971 Nature New Biol. 7 Apr. 162/1 Gordon Tomkins has proposed that mammalian cells may have a ‘pleiotypic’ control system ...
Oxford English Dictionary
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Membrane bound polyribosome
A polysome is when multiple ribosomes attach to the same strand of messenger ribonucleic acid.
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Why does the inhibition of translation initiation cause the accumulation of 80S ribosomal monosomes? As I have read in (1), inhibition of translation initiation will increase the number of 80S ribosomes while decreasi...
It will depend on the drug you are using. There is a pathway that forms the translational initiation complex that starts with binding the mRNA's cap, the small subunit scans to find the AUG, then the large subunit binds, and so on. The 80 S peaks on the density gradients are not vacant, they are poi...
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多核糖体
多核糖体(polyribosome,或简称为 polysome),又称聚核糖体、多聚核糖体,是一束或一组核糖体。这些核糖体可以附着在mRNA上,同时进行转译,使得蛋白质的转译速度大大加快。
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Ribosome profiling
This technique is also different from polysome profiling.
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superimpose
ˌsuperimˈpose, v. [f. super- 2 + impose v. after superimposition.] 1. trans. To impose or place (one object) on or upon another; to lay above or on the top. a. gen.1823 H. J. Brooke Introd. Crystallogr. 291 The first plate of molecules which is superimposed on the primary plane. 1851 D. Wilson Preh....
Oxford English Dictionary
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عديد الريبوسومات
عديد الريبوسومات (بالإنجليزية: polyribosome) أو عديد الجسيمات (بالإنجليزية: polysome) هو مجموعة من الريبوسومات متصلة بجزيء واحد من الرنا المرسال كالخرز
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Bacterial translation
The complex of one mRNA and a number of ribosomes is called a polysome or polyribosome.
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