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pluripotency

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pluripotency
pluripotency Biol. (plʊərɪˈpəʊtənsɪ) [ad. G. pluripotenz: see pluri- and potency.] The property of being pluripotential; = pluripotence, pluripotentiality.1927 Biol. Abstr. I. 217/1 The term pluripotency is used to describe the virtual ability possessed by every organism, under certain conditions, t... Oxford English Dictionary
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Pluripotency (biological compounds)
The pluripotency of biological compounds describes the ability of certain substances to produce several distinct biological responses. Interferon gamma represents an example of pluripotency in itself. wikipedia.org
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Improved Derivation Efficiency and Pluripotency of Stem Cells ... - PLOS
NtES cells exhibited typical ES characteristics and up-regulated Sox2 expression in media with either small-molecule. Higher rates of full term ntES-4N pup were generated by the supplementation of PD or SC1. We obtained the highest efficiency of ntES-4N pup generation ever reported from this strain by supplementing ES medium with SC1.
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pluripotent
pluripotent, a. Biol. (plʊərɪˈpəʊtənt) [f. pluri- + potent a.1 and n.2] = next. Hence pluriˈpotence = pluripotency.1942 J. Needham Biochem. & Morphogenesis ii. 228 The retention of pluripotence through many cleavages, followed by separation of blastomeres. Ibid. iii. 435 They are at first pluripoten... Oxford English Dictionary
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Developmental pluripotency associated 2
Developmental pluripotency-associated protein 2 is a protein that in humans is encoded by the DPPA2 gene. References Further reading wikipedia.org
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pluripotential
pluripotential, a. Biol. (plʊərɪpəʊˈtɛnʃəl) [f. pluri- + potential a. and n.] Of a cell, tissue, or organism: capable of developing in any of various directions; = multipotential s.v. multi- 1 a.1925 Arch. Neurol. & Psychiatry (Chicago) XIII. 468 Phylogenetically considered, this structure is a plur... Oxford English Dictionary
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Stimulus-triggered acquisition of pluripotency
Stimulus-triggered acquisition of pluripotency (STAP) was a proposed method of generating pluripotent stem cells by subjecting ordinary cells to certain Additionally, these mice produced healthy offspring, thereby demonstrating germline transmission which is "a strict criterion for pluripotency as well wikipedia.org
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SON (gene)
is known about the regulation of pluripotency throughout the process of splicing. The factor SON is identified as essential for the maintenance of this pluripotency. wikipedia.org
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Role of Fbx15 in ES cells and its use in assaying for iPS cells (Yamanaka paper and others)? I am trying to understand the assay for iPS cells in the Takahashi & Yamanaka 2006 paper. They inserted a beta-geo cassette...
Another paper from Yamanaka's group explains Fbx15. It says: > Inactivation of Oct3/4 in ES cells led to rapid extinction of Fbx15 expression. > > Fbx15-null ES cells were normal in morphology, proliferation, and differentiation. These data demonstrate that Fbx15 is a novel target of Oct3/4 but is d...
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Oct-4
It plays a vital role in determining the fates of both inner mass cells and embryonic stem cells and has the ability to maintain pluripotency throughout In contrast, repression of Oct-4 induces loss of pluripotency and dedifferentiation to trophectoderm. wikipedia.org
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Can/Have cancer cells be/been used in stem cell culture lines? Since Cancer cells have unlimited growth potential, can they be induced towards totipotency and pluripotency? If so, can cancer cells be used in stem cell...
Cancer cells can be and are used in cell culture. HeLa cells were the first human cell line to be grown in culture and they were derived from a cervical tumor. That being said, Cancer cell lines would not _necessarily_ be used for stem cell work. They have sustained too many mutations to study the t...
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FOXD3
Previously, Foxd3 was demonstrated to be required in maintaining pluripotency in mouse embryonic stem cells. While there is no ambiguity that Foxd3 plays an important role regulating the transition from naive to primed pluripotency state, the two models show a wikipedia.org
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Mir-720 microRNA precursor family
miR-720 Targeting miR-720 was shown to target the pluripotency factor Nanog and to upregulate DNMTs. miR-720 controlled stem cell phenotype, proliferation Repression of the pluripotency factor Nanog and upregulation of DNMTs in dental pulp cells by miR-720 initiated odontoblastic differentiation. wikipedia.org
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EZH1
EZH1 also complements EZH2 in maintaining stem cell identity and executing pluripotency. References Further reading wikipedia.org
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FOXP1
It was shown that the embryonic stem cell (ESC)-specific isoform of FOXP1 stimulates the expression of transcription factor genes required for pluripotency This isoform also promotes the maintenance of ESC pluripotency and contributes to efficient reprogramming of somatic cells into induced pluripotent stem wikipedia.org
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