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plasminogen
plasminogen Physiol. (plæzˈmɪnədʒən) [f. prec. + -ogen.] The inactive precursor, present in blood, of the enzyme plasmin.1945 [see prec.]. 1962 Lancet 27 Jan. 191/1 The presence of plasminogen activator in tissue suggests that it may have a role in the removal of unwanted fibrin. 1968, 1976 [see pre...
Oxford English Dictionary
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Plasminogen (medication)
Plasminogen, sold under the brand name Ryplazim, is a biologic medication for the treatment of hypoplasminogenemia (plasminogen deficiency type 1). pediatric participants with plasminogen deficiency type 1.
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Plasminogen activator
There are two main plasminogen activators: urokinase (uPA) and tissue plasminogen activator (tPA). Plasminogen activators are inhibited by plasminogen activator inhibitor-1, plasminogen activator inhibitor-2, and protein C inhibitor.
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Plasminogen activator inhibitor-2
Plasminogen activator inhibitor-2 (placental PAI, SerpinB2, PAI-2), a serine protease inhibitor of the serpin superfamily, is a coagulation factor that inactivates tissue plasminogen activator and urokinase.
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Plasminogen activator inhibitor-1
Plasminogen activator inhibitor-1 (PAI-1) also known as endothelial plasminogen activator inhibitor (serpin E1) is a protein that in humans is encoded Function
PAI-1's main function entails the inhibition of urokinase plasminogen activator (uPA), an enzyme responsible for the cleavage of plasminogen
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Plasminogen activator Pla
Plasminogen activator Pla () is an enzyme. hydrolysed by the mammalian u-plasminogen activator and t-plasminogen activator.
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Staphylokinase
Staphylokinase interacts with plasminogen to form a 1:1 complex that exposes the active site of the plasminogen molecule. There is little or no homology between the primary structure of Sak and other plasminogen activators.
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5327 - Gene ResultPLAT plasminogen activator, tissue type [ (human)]
Summary. This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the ...
www.ncbi.nlm.nih.gov
Tissue-type plasminogen activator
Tissue plasminogen activator also plays a role in cell migration and tissue remodeling. Lastly, tPA can bind plasminogen, cleaving off the bound plasmin from it.
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بلازمين
البلازمين يفرز على شكل زايموجين ويسمى بلازموجين plasminogen من الكبد إلى الدورة الدموية. البلازمينوجين يتحول إلى البلازمين activation by tissue عبر انزيمات منها منشط البلازمينوجين النسيجي tissue plasminogen activator.
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Soluble urokinase plasminogen activator receptor
Soluble urokinase plasminogen activator receptor (suPAR) (NCBI Accession no. uPAR has cleavage sites for several proteases in the linker region (chymotrypsin, elastase, matrix metalloproteases, cathepsin G, plasmin, urokinase plasminogen
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PLG (消歧义)
纤溶酶(Plasminogen)
(Polynesian Leaders Group)
法政汇思(Progressive Lawyers Group)
(Progressive Librarians Guild)
(Prospect Lefferts Gardens),位于美国纽约布鲁克林区。
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Hypoplasminogenemia
Hypoplasminogenemia, also known as plasminogen deficiency type 1, is a genetic disorder characterized by a lack of the protein plasminogen, which is responsible References
External links
Congenital plasminogen deficiency MeSH, National Library of Medicine
Plasminogen Deficiency Foundation
Genetic diseases
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Urokinase
The protein encoded by this gene converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. zfuPA-a and zfuPA-b are poor activators of human plasminogen, while human uPA is a poor activator of salmon plasminogen.
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Urokinase receptor
plasminogen activation to the immediate vicinity of the cell membrane. Thus inhibitors of the various components of the plasminogen activation system have been sought as possible anticancer drugs.
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