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neurotrophic
neurotrophic, a. (njʊərəʊˈtrəʊfɪk, -ˈtrɒfɪk) [f. neuro- + -trophic.] Of or pertaining to the control of cells exerted by nervous tissue, esp. in relation to cellular nutrition.1887 T. W. Mills in Med. Record 22 Oct. 529/2, I propose..to substitute for mechanical explanations as applied to cardiac pa...
Oxford English Dictionary
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Neurotrophic electrode
Assembly
Most of the neurotrophic electrode is made by hand. Kennedy adapted the neurotrophic electrode to read local field potentials (LFPs).
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Neurotrophic keratitis
Neurotrophic keratitis (NK) is a degenerative disease of the cornea caused by damage of the trigeminal nerve, which results in impairment of corneal sensitivity Neurotrophic keratitis is classified as a rare disease, with an estimated prevalence of less than 5 in 10,000 people in Europe.
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Neurotrophic factors
Most neurotrophic factors belong to one of three families: (1) neurotrophins, (2) glial cell-line derived neurotrophic factor family ligands (GFLs), and Neurotrophins
Brain-derived neurotrophic factor
Brain-derived neurotrophic factor (BDNF) is structurally similar to NGF, NT-3, and NT-4/5, and shares
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Neurotrophic factor receptor
Neurotrophic factor receptors or neurotrophin receptors are a group of growth factor receptors which specifically bind to neurotrophins (neurotrophic factors Two classes of neurotrophic factor receptors are the p75 and the "Trk" families of Tyrosine kinases receptors.
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en.wikipedia.org
Neurotrophic hypothesis of depression
The neurotrophic hypothesis of depression proposes that major depressive disorder (MDD) is caused, at least partly, by impaired neurotrophic support. See also
Neurotrophic factors
Brain derived neurotrophic factor
Neuroplasticity
Neurogenesis
Neurogenesis hypothesis of depression
References
wikipedia.org
en.wikipedia.org
[PDF] Brain-derived Neurotrophic Factor (BDNF ... - Semantic Scholar
In cultured hippocampal neurons, application of BDNF for 15 min decreased the percentage of moving mitochondria in axons, a process dependent on the activation of the TrkB receptor and its downstream PI3K and phospholipase-Cγ signaling pathways, which suggests that mitochondrial transport and distribution play essential roles in BDNF-mediated synaptic transmission. Background: Appropriate ...
www.semanticscholar.org
Brain-derived Neurotrophic Factor (BDNF)-induced ... - ScienceDirect
FM 1-43 staining was carried out as described previously with a few modifications (25, 26 27).For labeling active presynaptic boutons, the neurons were stimulated by superfusing with the hyperkalemic solution (31.5 m m NaCl, 90 m m KCl, 2 m m CaCl 2, 2 m m MgCl 2, 25 m m HEPES, 30 m m glucose) containing FM 1-43 (5 μ m) for 45 s.During the loading period, the dye was rapidly taken up into ...
www.sciencedirect.com
Brain-derived neurotrophic factor (BDNF)-induced mitochondrial motility ...
Europe PMC is an archive of life sciences journal literature.
europepmc.org
Brain-derived Neurotrophic Factor (BDNF)-induced Mitochondrial Motility ...
Background: Appropriate mitochondrial transport and localization are highly associated with neuronal activities.Results: BDNF induces mitochondrial motility arrest via Miro1 binding with Ca2+, which facilitates BDNF-enhanced neurotransmitter release.Conclusion: BDNF-regulated mitochondrial motility is essential for BDNF-enhanced synaptic transmission.Significance: These results provide novel ...
www.jbc.org
Method for expressing recombinant neurotrophic factor fusion protein ...
A neurotrophic factor and fusion protein technology, applied in the field of functional proteins, can solve the problems of complicated operation, low expression level, and low activity, and achieve the effects of reducing production costs, improving secretion efficiency, and good biological activity
eureka.patsnap.com
Brain-derived neurotrophic factor (BDNF)-induced ... - Europe PMC
Introduction. Mitochondria are important organelles with multiple functions, including ATP production, the maintenance of intracellular Ca 2+ homeostasis, and the regulation of apoptosis. In neurons, proper mitochondrial trafficking and distribution along neurites are involved in synaptic plasticity modulation such as presynaptically neurotransmitter release, postsynaptically membrane ...
europepmc.org
The Role of Skeletal Muscle-synthesized Brain-derived Neurotrophic ...
It is hypothesized that skeletal muscle-BDNF is required for normal retrograde transport of neurofilament-H, the vesicular protein synaptophysin, and mitochondria in motorneuron axons, and investigated potential accumulation of mitochondria at the presynapse due to a decrease in retrogrades of old and or damaged mitochondria being trafficked to the cell body. Brain-derived neurotrophic factor ...
www.semanticscholar.org
Figure 1 from Brain-derived Neurotrophic Factor (BDNF)-induced ...
FIGURE 1. BDNF induces more mitochondria into the stationary pool without affecting other organelles. A and B, representative static images of mitochondria in neurites before (A) and after (B) BDNF treatment. A and B , representative kymographs showing decreased mitochondrial movement in neurites upon BDNF treatment (B ) compared with pretreatment (A ). Scale bar, 10 m; height, 5 min. C ...
www.semanticscholar.org
Figure 8 from Brain-derived Neurotrophic Factor (BDNF)-induced ...
FIGURE 8. Requirement of Miro1 for BDNF-enhanced neurotransmitter release. A, experimental protocol for FM 1-43 staining and destaining of synaptic vesicles. ADVASEP-7 was used for enhanced removal of the dye from the external medium. Two images were taken after staining (I) and destaining (II), respectively. The difference in the number of FM 1-43-stained boutons between images (I and II ...
www.semanticscholar.org