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myeloblast
myeloblast Anat. (ˈmaɪələʊblɑːst, -æ-) [a. G. myeloblast (O. Naegeli 1900, in Deutsche med. Wochenschr. 3 May 289/1): see myelo- and -blast.] Any of the immature cells (approximately 15 microns in diameter, with large nuclei and a small amount of densely staining cytoplasm) which are confined to the...
Oxford English Dictionary
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Myeloblast
The myeloblast is a unipotent stem cell which differentiates into the effectors of the granulocyte series. It is found in the bone marrow. Function
Granulopoiesis consists of 5 stages, in which the myeloblast is the first recognizable cell.
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Promyelocyte
A promyelocyte (or progranulocyte) is a granulocyte precursor, developing from the myeloblast and developing into the myelocyte. The nucleus of a promyelocyte is approximately the same size as a myeloblast but their cytoplasm is much more abundant.
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myelocyte
myelocyte (ˈmaɪələʊsaɪt) [f. myelo- + -cyte.] 1. The nucleus of a ganglionic nerve-cell.1866 A. Flint Princ. Med. 51 Myeolocytes [sic], or cells found in the substance of the brain, the spinal cord, and in one of the beds of the retina. 1889 Nature 21 Nov. 72/1 The nervous elements termed myelocytes...
Oxford English Dictionary
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Granulopoiesis
The first unipotent cell in granulopoiesis is a myeloblast. The first cell that starts to resemble a granulocyte is a myeloblast.
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Proerythroblast
In histology, it is very difficult to distinguish it from the other "-blast" cells (lymphoblast, myeloblast, monoblast, and megakaryoblast). The distinguished feature of pro erythroblast to its corresponding myeloblast in granulocytic series is that it carries more basophilic peripheral cytoplasm
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mono-
mono- (mɒnəʊ, məˈnɒ) before a vowel often mon-, repr. Gr. µονο-, combining form of µόνος, alone, only, sole, single, occurring in a number of words adopted from existing Greek compounds (as monarch, monody, monogamy, monogram, monologue, monopoly), and hence used to form words, mostly scientific and...
Oxford English Dictionary
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Myelopoiesis
In this process it first transforms from a common myeloblast (myeloid progenitor) to a common promyelocyte.
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Myeloid tissue
or platelets (the common myeloid progenitor, that is, CMP or CFU-GEMM), or in a narrower sense also often used, specifically from the lineage of the myeloblast
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Acute myeloblastic leukemia with maturation
This acute disease prevents bone marrow cells from properly maturing, thus causing an accumulation of immature myeloblast cells in the bone marrow. in acute myeloid leukemia have a higher loss of function and thus, a higher inability to carry out normal functions than those more developed immature myeloblast
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Myeloid leukemia
See also
Hematological malignancies
Myeloblast
transient myeloproliferative disease
External links
Leukemia
lt:Mieloma
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CBFB
This prevents proper differentiation of blood cells, leading to the formation of Myeloblast.
References
External links
Further reading
Oncogenes
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Acute myelomonocytic leukemia
A myeloblast is an immature precursor cell that will change into a monocyte, healthy white blood cell. In AML, Myeloblast do not mature but grow and multiply with regulation.
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Acute myeloid leukemia
Pathophysiology
The malignant cell in AML is the myeloblast. In normal development of blood cells (hematopoiesis), the myeloblast is an immature precursor of myeloid white blood cells; a normal myeloblast will mature
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Acute erythroid leukemia
M6b (Pure erythroid leukemia)
In rare cases the erythroid lineage is the only obvious component of an acute leukemia; a myeloblast component is not apparent M6c (Erythroleukemia and Pure erythroid leukemia)
Myeloblast- and proerythroblast-rich mixed variant.
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