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monoamine

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monoamine
monoamine Biochem. (mɒnəʊˈeɪmiːn) [f. mono- 2 + amine.] a. Any compound having a single (primary, secondary, or tertiary) amine group in its molecule, spec. one which is a neurohormone; = monamine.1951 I. L. Finar Org. Chem. I. xiii. 260 Diamines may be prepared by methods similar to those for the m... Oxford English Dictionary
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Monoamine neurotransmitter
There, they can be repackaged into synaptic vesicles or degraded by the enzyme monoamine oxidase (MAO), which is a target of monoamine oxidase inhibitors See also Monoamine reuptake inhibitor Monoamine receptor Monoamine oxidase Monoamine transporter Monoamine Hypothesis Biogenic amine Trace amine wikipedia.org
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Monoamine Oxidase Inhibitors (MAOI) - Mechanism of Action ...
The molecular mechanism of this neuroprotective activity involves regulation of B-cell lymphoma/leukaemia 2 (BCL2) family proteins and protein kinase-dependent signalling pathways and interactions with glyceraldehyde-3-phosphate dehydrogenase and induction of some antioxidant enzymes. [Youdim, 2006] Reversible and selective
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Monoamine Oxidase Inhibitors (MAOI) - StatPearls - NCBI Bookshelf
Jul 17, 2023Mechanism of Action. Monoamine oxidase inhibitors are responsible for blocking the monoamine oxidase enzyme. The monoamine oxidase enzyme breaks down different types of neurotransmitters from the brain: norepinephrine, serotonin, dopamine, and tyramine. MAOIs inhibit the breakdown of these neurotransmitters thus, increasing their levels and ...
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Kinetics, mechanism, and inhibition of monoamine oxidase
Kinetics, mechanism, and inhibition of monoamine oxidase. J Neural Transm (Vienna)2018 Nov;125 (11):1659-1683. doi: 10.1007/s00702-018-1861-9. Epub 2018 Mar 7. Monoamine oxidases (MAOs) catalyse the oxidation of neurotransmitter amines and a wide variety of primary, secondary and tertiary amine xenobiotics, including therapeutic drugs.
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Monoamine precursor
Monoamine precursors are precursors of monoamines and monoamine neurotransmitters in the body. Administration of monoamine precursors can increase the levels of monoamine neurotransmitters in the body and brain. wikipedia.org
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Structures and Mechanism of the Monoamine Oxidase Family
The mechanism of oxidation of reduced MAO by O 2 has not been studied in detail. When monitored by stopped-flow absorbance, the reactions of reduced flavoprotein oxidases with O 2 are typically found to be single exponential processes with rate constants directly proportional to the O 2 concentration and no discernible intermediates.
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Does the Enzyme Monoamine Oxidase, Isoenzyme A have an allosteric modulatory site? Does the Enzyme Monoamine Oxidase, Isoenzyme A (MAO-A) have an allosteric modulatory site? I ask because I would like to know if it is...
I think an allosteric modulatory site has already been found, but it's not specific to Isoenzyme A, if that's what you were looking for. See these papers: < <
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Monoamine activity enhancer
rather potentiate impulse-evoked monoamine-release. Endogenous monoamine activity enhancers Monoamine activity enhancers can possess selectivity for enhancing the release of a certain monoamine over others wikipedia.org
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Monoamine reuptake inhibitor
A monoamine reuptake inhibitor (MRI) is a drug that acts as a reuptake inhibitor of one or more of the three major monoamine neurotransmitters serotonin , norepinephrine, and dopamine by blocking the action of one or more of the respective monoamine transporters (MATs), which include the serotonin transporter wikipedia.org
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Monoamine oxidase A
Monoamine oxidase A, also known as MAO-A, is an enzyme (E.C. 1.4.3.4) that in humans is encoded by the MAOA gene. Mutations in the MAOA gene results in monoamine oxidase deficiency, or Brunner syndrome. wikipedia.org
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Monoamine nuclei
Monoamine nuclei are clusters of cells that primarily use monoamine neurotransmitters to communicate. The raphe nuclei, ventral tegmental area, and locus coeruleus have been included in texts about monoamine nuclei. wikipedia.org
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TWI306027B - 3-amino-1-arylpropyl indoles as monoamine reuptake ...
TWI306027B TW094117705A TW94117705A TWI306027B TW I306027 B TWI306027 B TW I306027B TW 094117705 A TW094117705 A TW 094117705A TW 94117705 A TW94117705 A TW 94117705A TW I306027 B TWI306027 B TW I306027B Authority TW Taiwan Prior art keywords group compound phenyl optionally substituted alkyl Prior art date 2004-06-01 Application number TW094117705A
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As monoamine reuptake inhibitors 8-azabicyclo [3.2.1] octane derivative
The present invention relates to formula I 8-azabicyclo [3.2.1] octane derivative, wherein R1 is H or C1-5 alkyl; Y is O, S, or O (CH2) m; m is 1 or 2 ; n is 0 or 1; Ar1 is phenylene or pyridylene, said phenylene and pyridylene and 1,3-linked is 0, when n is 1 and Y is connected, when n is 0, Ar2 is connected with the phenylene or pyridyl optionally substituted with one or two substituents ...
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Monoamine transporter
Monoamine transporters (MATs) are proteins that function as integral plasma-membrane transporters to regulate concentrations of extracellular monoamine transporter (VMAT) Plasma membrane monoamine transporter (PMAT) Extraneuronal monoamine transporter (EMT) References External links Neurotransmitter wikipedia.org
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