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Kinase - Wikipedia
an enzyme that catalyzes the transfer of phosphate groups from high-energy, phosphate-donating molecules to specific substrates. en.wikipedia.org
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Definition of kinase - NCI Dictionary of Cancer Terms
A type of enzyme (a protein that speeds up chemical reactions in the body) that adds chemicals called phosphates to other molecules, such as sugars or ... www.cancer.gov
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Kinase - an overview | ScienceDirect Topics
Kinases are enzymes involved in intracellular signal transduction. Kinases play key roles in generating the cellular response to external signals detected at ... www.sciencedirect.com
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kinase
kinase Biochem. (ˈkaɪneɪz, -s) [f. Gr. κιν-εῖν to move + -ase.] a. Any substance which converts an inactive precursor (a zymogen) into an active enzyme.1902 W. H. Thompson tr. Pawlow's Work of Digestive Glands ix. 160 When a tube was introduced into the fistula, and the succus entericus afterwards c... Oxford English Dictionary
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Protein Kinases | Cell Signaling Technology
Protein Kinases are key regulators of cell function that constitute one of the largest and most functionally diverse gene families. www.cellsignal.com
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Protein kinase - Wikipedia
A protein kinase is a kinase which selectively modifies other proteins by covalently adding phosphates to them (phosphorylation) en.wikipedia.org
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MAP kinase kinase kinase
Mitogen Activated Protein (MAP) kinase kinase kinase (MAPKKK, MKKK, M3K, or, MAP3K) is a serine/threonine-specific protein kinase which acts upon MAP kinase Subsequently, MAP kinase kinase activates MAP kinase. wikipedia.org
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KINASE Definition & Meaning - Merriam-Webster
: any of various enzymes that catalyze the transfer of phosphate groups from a high-energy phosphate-containing molecule (such as ATP) to a substrate www.merriam-webster.com
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Kinase | Definition, Biology, & Function | Britannica
Kinase, an enzyme that adds phosphate groups to other molecules. A large number of kinases exist, the human genome alone containing hundreds of ... www.britannica.com
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Protein Kinase Inhibitors - LiverTox - NCBI Bookshelf
The kinase inhibitors are a large group of unique and potent antineoplastic agents which specifically target protein kinases that are altered in ... www.ncbi.nlm.nih.gov
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Kinase assays | BMG LABTECH
Kinases are a large group of enzymes which are the focus of 1/3 of all drug development efforts due to their association with multiple ... www.bmglabtech.com
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why is janus kinase named such a kinase
Janus kinase is a family of intracellular, non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway.
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MAP kinase kinase kinase kinase
Mitogen-activated protein kinase kinase kinase kinase (MAP4K) is a family of proteins involved in cellular signal transduction. MAP kinase kinase MAP kinase kinase kinase List of unusual biological names References Protein families wikipedia.org
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Cyclin-dependent kinase - Wikipedia
A cyclin-dependent kinase inhibitor (CKI) is a protein that interacts with a cyclin-CDK complex to block kinase activity, usually during G1 or in response to signals from the environment or from damaged DNA. [1] In animal cells, there are two major CKI families: the INK4 family and the CIP/KIP family. [1]
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What for a Kinase Assay? I am wondering why to use a kinase assay, since we can extract the proteins from cells and then do a Western with the specific antibodies we want to use.
Instead, they'll use recombinant kinase and substrate peptides, with a variety of readout systems to choose from. necessary to activate the kinase _in vitro_ , lack of a good model system, and more.
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