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inosine
inosine, n. Biochem. (ˈɪnəʊsiːn) Also (formerly) -in. [a. or ad. G. Inosin (Haiser & Wenzel 1909, in Monatshefte f. Chemie XXIX. 166), f. Inosinsäure inosinic acid.] A crystalline nucleoside, C5H9O4·C5H3N4O , in which the base is hypoxanthine and the sugar ribose, and which is used in kidney transpl...
Oxford English Dictionary
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Inosine
Inosine monophosphate is oxidised by the enzyme inosine monophosphate dehydrogenase, yielding xanthosine monophosphate, a key precursor in purine metabolism The main problem of using inosine and/or inosine-5-monophosphate as feeding attractants is their high cost.
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Inosine pranobex
Inosine pranobex (BAN; also known as inosine acedoben dimepranol (INN) or methisoprinol) is an antiviral drug that is a combination of inosine and dimepranol Inosine pranobex has no effect on viral particles itself. Instead, it acts as an immunostimulant, an analog of thymus hormones.
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Inosine kinase
In enzymology, an inosine kinase () is an enzyme that catalyzes the chemical reaction
ATP + inosine ADP + IMP
Thus, the two substrates of this enzyme are ATP and inosine, whereas its two products are ADP and IMP.
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Inosine nucleosidase
In enzymology, an inosine nucleosidase () is an enzyme that catalyzes the chemical reaction
inosine + H2O D-ribose + hypoxanthine
Thus, the two substrates The systematic name of this enzyme class is inosine ribohydrolase. Other names in common use include inosinase, and inosine-guanosine nucleosidase.
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Inosine triphosphate
Inosine triphosphate (ITP) is an intermediate in the purine metabolism pathway, seen in the synthesis of ATP and GTP. ITP is processed by the enzyme inosine triphosphate pyrophosphatase (ITPA), which turns it into inosine monophosphate (IMP), to avoid incorporation into
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Inosine monophosphate synthase
ATIC encodes an enzyme which generates inosine monophosphate from aminoimidazole carboxamide ribonucleotide.
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Inosine monophosphate dehydrogenase
Inosine pranobex
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Inosine-5′-monophosphate dehydrogenase
Inosine-5′-monophosphate dehydrogenase (IMPDH) is a purine biosynthetic enzyme that catalyzes the nicotinamide adenine dinucleotide (NAD)-dependent oxidation of inosine monophosphate (IMP) to xanthosine monophosphate (XMP), the first committed and rate-limiting step towards the de novo biosynthesis of guanine
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摇摆碱基对
在分子生物学中,摇摆碱基对是RNA分子中不遵守沃森-克里克碱基配对规则的碱基对 四个主要摆动碱基对是鸟嘌呤-脲嘧啶(guanine-uracil,G-U)、次黄嘌呤-脲嘧啶(inosine-uracil,I-U)、肌苷-腺嘌呤(inosine-adenine,I-A)和肌苷-胞嘧啶(inosine-cytosine
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ITPA
ITPA (Inosine triphosphatase) هوَ بروتين يُشَفر بواسطة جين ITPA في الإنسان.
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IMPDH1
Inosine-5'-monophosphate dehydrogenase 1, also known as IMP dehydrogenase 1, is an enzyme that in humans is encoded by the IMPDH1 gene. IMPDH1 is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP).
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IMPDH2
Inosine-5'-monophosphate dehydrogenase 2, also known as IMP dehydrogenase 2, is an enzyme that in humans is encoded by the IMPDH2 gene. IMPDH2 catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate
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ITPA
Inosine triphosphate pyrophosphatase is an enzyme that in humans is encoded by the ITPA gene, by the rdgB gene in bacteria E.coli and the HAM1 gene in Clinical significance
Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency.
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Adenosine-phosphate deaminase
Ultimately, this produces 5'-IMP (Inosine monophosphate) and NH3 (ammonia). This results in binding 5'-IMP is then catalyzed by Inosine-5'-monophosphate dehydrogenase (IMPDH), facilitating guanine nucleotide biosynthesis.
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