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heterologous
heterologous, a. (-ˈɒləgəs) [f. Gr. ἑτερο- hetero- + λόγ-ος ratio, relation, etc. + -ous.] Having a different relation, or consisting of different elements; not corresponding: opp. to homologous. spec. a. Path. Of a different formation from that of the normal tissue of the part.1822–34 Good's Study ...
Oxford English Dictionary
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Heterologous
The term heterologous has several meanings in biology. In a heterologous association, each protomer contributes a different set of residues to the binding interface.
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Heterologous expression - Wikipedia
Heterologous expression refers to the expression of a gene or part of a gene in a host organism that does not naturally have the gene or gene fragment in question. Insertion of the gene in the heterologous host is performed by recombinant DNA technology.The purpose of heterologous expression is often to determine the effects of mutations and differential interactions on protein function.
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Examples of heterologous expression in human cell beside viral expression Usually, people are interested in expressing human proteins in fast-growing organisms like bacteria to yield a maximum of protein within a shor...
Besides research (as mentioned by mxwsn), there are a lot of actual protein based medicines and vaccines produced in human cell lines. One of the first mass cultures of a human cell line was in the monkey free production of a polio vaccine (source). Almost every researcher working in a molecular lab...
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Induction of diploid gynogenesis in southern flounder (Paralichthys ...
First, one must effectively exclude the contri bution of chromosomes from the heteroga metic sex, in this case the flounder sperm. In 2004, Luckenbach et al. [17] found that the lowest UV dosage ...
www.researchgate.net
Heterologous expression
Insertion of the gene in the heterologous host is performed by recombinant DNA technology. Moreover, unnatural heterologous protein buildup also leads to adverse host effects.
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Which terminology is better: Heterologous expression system or heterologous cell model? I am reading a journal paper and I have read that the authors expressed the extracellular domain of the protein NCAM2 which is no...
In other words, I would refer to the NCAM2 expression package as the "heterologous expression system", which is then integrated into the CHO platform in order to create a "heterologous cell model."
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heterologal
† heteˈrologal, a. Math. Obs. [f. as heterologous a. + -al1.] Applied to those terms in two or more ratios or fractions which do not correspond, as the antecedent or numerator of one, and the consequent or denominator of the other: opp. to homologal.1674 S. Jeake Arith. (1696) 48 The new Fraction..w...
Oxford English Dictionary
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Heterologous desensitisation
Heterologous desensitization may occur in cells that are grossly overstimulated for prolonged times by a certain agents. Receptor desensitization, whether heterologous or homologous, may contribute to human pathology.
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What are the advantages of heterologous expression systems? I am doing research in a lab and I am relatively new to wet lab work. Many experiments that people are doing in my lab include overexpressing a protein of in...
* It takes significant resources to establish a cell line. More efficient to use existing lines. * Often cell lines used for expression grow faster. This is why so many proteins are expressed in E coli - they only take a day to grow vs the week or two for mammalian cells, meaning you get a much fast...
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Heterologous vaccine
A homologous booster shot involves the administration of the same vaccine as previously administered, while a heterologous booster shot involves the administration In many cases such heterologous prime-boost can be more immunogenic than homologous prime-boost."
References
Further reading
Vaccination
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How broad are the conclusions that one can make from a heterologous expression experiment? I am studying whether a neural protein regulates the activity of the protein GSK3. I am using heterologous expression systems ...
GSK3 is interesting because as a kinase, it is itself regulated by its phosphorylation status (particularly by Akt in neurons). Therefore, more protein does not necessarily mean more activity. For example from E13.5 to E15.5 GSK3 levels do not change but activity steadily increases. Hence if you inc...
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Engineering Aspergillus nidulans for heterologous ent ... - Springer
The genetic locus AN1594 encodes ent-pimara-8(14),15-diene synthase (PbcA) in Aspergillus nidulans. We previously reported identification of a biosynthetic gene cluster for ent-pimara-8(14),15-diene (PD) production in A. nidulans. We demonstrated that this gene cluster was upregulated in a wild-type A. nidulans strain overexpressing the cluster-specific transcription factor, pbcR, and that ...
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WO2021093864A1 - Use of heterologous tissue cell composition for ...
Provided is the use of a heterologous tissue cell composition isolated and amplified from a specific tissue. The heterologous tissue cell composition is administered to tumor/cancer tissues of the similar or same histological grade via an intralesional route, which can induce the individual's rejection reaction to the transplanted heterologous tissue cell composition, and then stimulate the ...
patents.google.com
Ogataea methanolica
a yeast, it shares the advantages of molecular and genetic manipulations with Saccharomyces, and it has the added
advantage of 10- to 100-fold higher heterologous
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