Artificial intelligent assistant

epistatic

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epistatic
epistatic, a. Genetics. (ɛpɪˈstætɪk) [prob. f. epi- + Gr. στάσις standing, position, state, after hypostatic a., hypostasis; but cf. Gr. ἐπιστάτης one who is set over (see epistates), ἐπιστασία dominion; a derivation directly from ἐπιστάτικος of government, (also) standing still, or from ἐπίστασις e... Oxford English Dictionary
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Hypostatic gene
Example: In labrador retrievers, the chocolate coat colour is a result of homozygosity for a gene that is epistatic to the "black vs. brown" gene. wikipedia.org
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hypostatic
hypostatic, a. (hɪpəʊ-, haɪpəʊˈstætɪk) [ad. Gr. ὑποστατικ-ός pertaining to substance, substantial, personal (f. ὑποστατός set under, supporting); used as adj. to ὑπόστασις hypostasis; but the medical sense of the English word is not found in Greek.] 1. Theol. Of or pertaining to substance, essence, ... Oxford English Dictionary
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Epistasis
For example, the gene for total baldness is epistatic to the gene for brown hair. Since identification of epistatic pairs is challenging both computationally and statistically, some studies try to prioritize epistatic pairs. wikipedia.org
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epistasis
epistasis (ɛˈpɪstəsɪs) [Gr. ἐπίστασις a stopping, stoppage, (also) scum on urine, f. ἐϕιστάναι to stop, check.] 1. Med. a. The checking of any discharge, as of blood or menses. b. A pellicle that forms on the surface of urine after it has stood. rare—0[1849 F. Adams Genuine Wks. Hippocrates II. Apho... Oxford English Dictionary
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Epistasis and functional genomics
Systematic analysis of these epistatic interactions can provide insight into the structure and function of genetic pathways. Ryszard Korona and Lukas Jasnos showed that the epistatic effect is usually positive in Saccharomyces cerevisiae. wikipedia.org
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Supergene
Turner, therefore argue that supergenes arose in situ due to selection for correlated and epistatic traits, which just happened to have been possible to complex of tightly linked genes all acting in the immune system, but has no claim to be a supergene, even though the component genes very likely have epistatic wikipedia.org
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What indices can we use to describe fitness landscapes? We usually talk of smooth or rugged fitness landscape. * Are there any (standard) indices to measure the "structure" of fitness landscapes? * For example...
This paper uses 4 metrics for discreet landscapes. < Deviation from additivity: How much your genes interact (normalized). Fitness in a purely additive landscape with three genes, for example, is F=f(x)+g(y)+h(z) where f,g, and h are each functions of one variable (the x,y, and z "genes"/coordinates...
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Ino budgerigar mutation
Nor is the Ino mutation epistatic over the Cinnamon mutation—see below. The Ino mutation does not mask the Cinnamon mutation, these two genes being neither fully epistatic nor hypostatic to each other. wikipedia.org
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What problem does the Dobzhansky-Muller Model resolve? This page describes the Dobzhansky-Muller model and I can follow the illustration of the split leading to incompatible hybrids. But at the start of the page the ...
Hence, Dobzhansky and Muller (and Bateson) created this minimalist model involving only two loci with negative epistatic interactions.
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Overo
The frame overo gene can be masked by other white patterns, particularly tobiano, which is a dominant gene and epistatic to overo. When a tobiano allele is present, it is epistatic and often masks other patterns. wikipedia.org
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Quasi-linkage equilibrium
Kimura's original model showed that approaches a stable state rapidly if epistatic effects are small relative to recombination. wikipedia.org
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Diallel cross
heterotic groups, estimate general or specific combining ability, interactions with testing environments and years, or estimates of additive, dominant, and epistatic wikipedia.org
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Genetic variance
Genetic variance has three major components: the additive genetic variance, dominance variance, and epistatic variance. Epistatic variance involves an interaction between different alleles in different loci. wikipedia.org
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POU4F1
Pou4f1/Isl1 double mutant mice show strong epistatic effects in regulation of many downstream genes in the sensory neurons of double mutant mouse embryos wikipedia.org
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