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decamethonium

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1
decamethonium
decamethonium Pharm. (ˌdɛkəmɪˈθəʊnɪəm) [f. deca- + methonium.] A quaternary ammonium cation, [(CH3)3N(CH2)10N(CH3)3]++; also, the bromide or iodide salt of this, used as a muscle relaxant.1949 G. Organe in Lancet 7 May 774/2 Decamethonium iodide (C 10) is a stable, neutral, non-irritant muscle relax... Oxford English Dictionary
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Decamethonium
In the process of binding, decamethonium activates (depolarizes) the motor endplate - but since the decamethonium itself is not degraded, the membrane Decamethonium was used clinically in the UK for many years, but it is now available only for research purposes. wikipedia.org
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suxamethonium
suxamethonium Pharm. (ˌsʌksəmɪˈθəʊnɪəm) [f. sux- + methonium.] = succinylcholine. Also suxamethonium bromide, suxamethonium chloride, suxamethonium iodide.1953 J. H. Gaddum Pharmacology (ed. 4) xi. 230 Suxamethonium iodide..also causes brief neuromuscular block. 1963 [see decamethonium]. 1977 Lancet... Oxford English Dictionary
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Hexamethonium
See also Decamethonium References Nicotinic antagonists Quaternary ammonium compounds wikipedia.org
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methonium
methonium Pharm. (mɪˈθəʊnɪəm) [f. meth- + -onium.] Any of various polymethylene bistrimethylammonium cations, [(CH3)3N(CH2)xN(CH3)3]2+ (where x is an integer), or salts of these ions, some of which are used as ganglionic blocking agents in the treatment of hypertension.[1949: cf. decamethonium, hexa... Oxford English Dictionary
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Doxacurium chloride
Ironically, laudexium itself was invented by a cross-combination between the prototypical non-depolarizing agent, d-tubocurarine and the depolarizing agent, decamethonium recurarizing" effects seen with tubocurarine and, more importantly, the absence of a depolarizing mechanism of action as seen with succinylcholine and decamethonium wikipedia.org
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fasciculation
fasciculation (fəˌsɪkjuːˈleɪʃən) [f. fasciculate v.: see -ation.] a. The state of being fasciculate. b. That which is fasciculated. c. Physiol. [f. fasciculus.] Uncoordinated twitching of a muscle, esp. that involving the simultaneous contraction of whole bundles or fasciculi of muscle fibres.1938 B... Oxford English Dictionary
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Neuromuscular-blocking drug
atoms between methonium heads as decamethonium. Succinylcholine has a 10-atom distance between its N atoms, like decamethonium. wikipedia.org
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Candicine
researchers concluded that the effects on frog tissue of candicine most closely resembled those of the well-known depolarizing neuromuscular-blocking drug decamethonium wikipedia.org
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hexa-
hexa- (hɛksə) before a vowel hex-, combining form of Gr. ἕξ six, freely used in Greek, and forming the initial element in various modern technical words, some adopted from Greek, others formed from Greek elements or on Greek analogies. In Chem. it indicates the presence of six atoms of some element,... Oxford English Dictionary
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Eleanor Zaimis
methonium compounds and synthesized the remaining members of what is referred to as the methonium series, including compounds such as hexamethonium and decamethonium wikipedia.org
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Pancuronium bromide
Decamethonium and suxamethonium also have this same interonium distance. wikipedia.org
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Mivacurium chloride
Ironically, laudexium itself was invented by a cross-combination between the prototypical non-depolarizing agent, d-tubocurarine and the depolarizing agent, decamethonium recurarizing" effects seen with tubocurarine and, more importantly, the absence of a depolarizing mechanism of action as seen with succinylcholine and decamethonium wikipedia.org
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List of drugs: De
de dea-deb deanol aceglumate (INN) Deapril-ST deboxamet (INN) debrisoquine (INN) debropol (INN) dec-def Deca-Durabolin Decabid Decaderm decamethonium wikipedia.org
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Patrick Humphrey
His doctoral thesis concerned the activities of decamethonium at the neuromuscular junction, and was supervised by Richard Creese. wikipedia.org
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