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cataplexy
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cataplexy
cataplexy (ˈkætaplɛksɪ) [In Ger. kataplexie, mod. f. Gr. κατάπληξις (Hippocrates) stupefaction, f. καταπλήσσ-ειν to strike down with terror or the like.] The temporary paralysis or hypnotic state in animals when ‘shamming death’.1883 Romanes Ment. Evol. Anim. xviii. 308 The researches of Professor P...
Oxford English Dictionary
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Cataplexy
Cataplexy without narcolepsy is rare and the cause is unknown. Treatment
Cataplexy is treated with medications.
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Cataplexy: Causes, Symptoms, and Treatment - Sleep Foundation
Jan 16, 2024Cataplexy is a symptom of narcolepsy, involving brief muscle weakness. Cataplexy is closely linked to a loss of hypocretin, an important role regulator of wakefulness in the brain. If you experience sudden muscle weakness, consult a healthcare provider for diagnosis and treatment. Cataplexy is a sudden muscle weakness that occurs while a person ...
www.sleepfoundation.org
cataplectic
cataˈplectic, a. [mod. ad. Gr. καταπληκτικ-ός fitted to strike or be stricken down: see cataplexy.] Of or pertaining to cataplexy.1883 Romanes Ment. Evol. Anim. xviii. 309 Such an animal as a wood-louse or death-watch, which fall into a kataplectic state immediately on being alarmed.
Oxford English Dictionary
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Pitolisant
It was granted orphan drug designation for the treatment of narcolepsy, fast track designation for the treatment of excessive daytime sleepiness and cataplexy in people with narcolepsy, and breakthrough therapy designation for the treatment of cataplexy in people with narcolepsy.
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Thomas Scammell
an American neurologist, known for his research in sleep medicine pertaining to neurobiology of sleep and sleep disorders, particularly narcolepsy and cataplexy since 2012, where he has a laboratory which conducts research on the neurobiology of sleep and the neural basis of sleep disorders such as narcolepsy and cataplexy
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CHKB (gene)
neurological disabling sleep disorder, characterized by excessive daytime sleepiness, sleep fragmentation, symptoms of abnormal rapid-eye-movement (REM) sleep, cataplexy Cataplexy is a sudden loss of muscle tone triggered by emotions, which is the most valuable clinical feature used to diagnose narcolepsy.
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en.wikipedia.org
Xywav
Xywav, is a medication used to treat cataplexy or excessive daytime sleepiness (EDS). Medical uses
Xywav is indicated for the treatment of cataplexy in people aged seven years of age and older with narcolepsy.
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en.wikipedia.org
Autosomal dominant cerebellar ataxia, deafness, and narcolepsy
is a rare progressive genetic disorder that primarily affects the nervous system and is characterized by sensorineural hearing loss, narcolepsy with cataplexy Presentation
Usually, people with this disorder have ataxia, mild–moderate sensorineural hearing loss, narcolepsy, and cataplexy.
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en.wikipedia.org
Laughter-induced syncope
Laughter-induced syncope should not be confused with cataplexy, a sudden loss of muscle tone triggered by strong emotions, particularly laughter. Unlike syncope, there is no loss of consciousness in cataplexy, which affects 65-75% of patients with narcolepsy.
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en.wikipedia.org
Narcolepsy
Narcolepsy paired with cataplexy is evidenced to be an autoimmune disorder. These experiences of cataplexy can be brought on by strong emotions. In some cases, cataplexy may resemble epileptic seizures.
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TRIB2
levels of autoantibodies against TRIB2 in Hcrt neurons (in lateral and posterior hypothalamus) seem also closely related to some cases of narcolepsy + cataplexy
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Penfield mood organ
A "Penfield wave transmitter" is also described in the book, as a weapon for inducing cataplexy.
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Barbara E. Jones
influence of inhibitory GABA neurons on sleep states and the activity of hypocretins/orexins neurons as key regulators of waking and narcolepsy with cataplexy
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Idiopathic hypersomnia
Causes
Unlike narcolepsy with cataplexy, which has a known cause (autoimmune destruction of hypocretin-producing neurons), the cause of IH is largely The prevalence of narcolepsy (with cataplexy) is estimated between 1/3,300 and 1/5,000.
wikipedia.org
en.wikipedia.org