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-sterol
-sterol, suffix Biochem. (stərɒl) [f. cholesterol.] A formative element in the names of many sterols, as in ergosterol, phytosterol. Oxford English Dictionary
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Sterol
Sterol is an organic compound with formula , whose molecule is derived from that of gonane by replacement of a hydrogen atom in position 3 by a hydroxyl group. It is therefore an alcohol of gonane. More generally, any compounds that contain the gonane structure, additional functional groups, and/or ... wikipedia.org
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sterol
sterol Biochem. (ˈstɪərɒl, ˈstɛrɒl) [The ending of cholesterol, ergosterol, etc., used substantively.] Any of a class of solid, unsaturated steroid alcohols that occur naturally both free and in combination as esters or glycosides and are classified according to their origin as mycosterols, phytoste... Oxford English Dictionary
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Sterol esterase
The enzyme sterol esterase (EC 3.1.1.13) catalyzes the reaction a sterol ester + H2O a sterol + a fatty acid This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is steryl-ester acylhydrolase. Other names in common use include chol... wikipedia.org
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Sterol ester
Sterol esters are a heterogeneous group of chemical compounds. They are created when the hydroxyl group of a sterol and a fatty acid undergo an esterification reaction. They can be found in trace amounts in every cell type but are highly enriched in foam cells and are common components of human skin... wikipedia.org
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Sterol 14-demethylase
In enzymology, a sterol 14-demethylase () is an enzyme of the Cytochrome P450 (CYP) superfamily. It is any member of the CYP51 family. It catalyzes a chemical reaction such as: obtusifoliol + 3 O2 + 3 NADPH + 3 H+ 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + formate + 3 NADP+ + 4 H2O Th... wikipedia.org
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Sterol O-acyltransferase
Sterol O-acyltransferase (also called Acyl-CoA cholesterol acyltransferase, Acyl-CoA cholesterin acyltransferase or simply ACAT) is an intracellular protein located in the endoplasmic reticulum that forms cholesteryl esters from cholesterol. Sterol O-acyltransferase catalyzes the chemical reaction: ... wikipedia.org
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Sterol 24-C-methyltransferase
In enzymology, a sterol 24-C-methyltransferase () is an enzyme that catalyzes the chemical reaction S-adenosyl-L-methionine + 5alpha-cholesta-8,24-dien-3beta-ol S-adenosyl-L-homocysteine + 24-methylene-5alpha-cholest-8-en-3beta-ol Thus, the two substrates of this enzyme are S-adenosyl methionine and... wikipedia.org
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Sterol 12alpha-hydroxylase
Sterol 12alpha-hydroxylase may refer to: 5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase, an enzyme 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase, an enzyme wikipedia.org
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A Medicinal Chemistry-Driven Approach Identified the Sterol Isomerase ...
1. INTRODUCTION. APC is a tumor suppressor in colorectal cancer. 1 Loss of function mutations in APC drive tumor growth by stabilizing the oncogenic transcription factor β-catenin. 2 APC mutations are found in over 85% of familial adenomatous polyposis (FAP) patients, 3 as well as over 80% of sporadic colorectal tumors; 4 approximately 65% of these mutations cluster between amino acid 1,286 ...
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Sterol 3beta-glucosyltransferase
In enzymology, a sterol 3beta-glucosyltransferase () is an enzyme that catalyzes the chemical reaction UDP-glucose + a sterol UDP + a sterol 3-beta-D-glucoside Thus, the two substrates of this enzyme are UDP-glucose and sterol, whereas its two products are UDP and sterol 3-beta-D-glucoside. This enz... wikipedia.org
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Diacylglycerol—sterol O-acyltransferase
In enzymology, a diacylglycerol-sterol O-acyltransferase () is an enzyme that catalyzes the chemical reaction 1,2-diacyl-sn-glycerol + sterol monoacylglycerol + sterol ester Thus, the two substrates of this enzyme are 1,2-diacyl-sn-glycerol and sterol, whereas its two products are monoacylglycerol a... wikipedia.org
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Triacylglycerol—sterol O-acyltransferase
In enzymology, a triacylglycerol---sterol O-acyltransferase () is an enzyme that catalyzes the chemical reaction triacylglycerol + a 3beta-hydroxysterol diacylglycerol + a 3beta-hydroxysterol ester Thus, the two substrates of this enzyme are triacylglycerol and 3beta-hydroxysterol, whereas its two p... wikipedia.org
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Phosphatidylcholine—sterol O-acyltransferase
In enzymology, a phosphatidylcholine---sterol O-acyltransferase () is an enzyme that catalyzes the chemical reaction phosphatidylcholine + a sterol 1-acylglycerophosphocholine + a sterol ester Thus, the two substrates of this enzyme are phosphatidylcholine and sterol, whereas its two products are 1-... wikipedia.org
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Sterol-sensing domain
A sterol-sensing domain (SSD) is a protein domain which consists of 180 amino acids forming five transmembrane segments capable of binding sterol groups. This type of domain is present in proteins involved in cholesterol metabolism and signalling. Function Sterol-sensing domains are present in vario... wikipedia.org
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