oxazole Chem.
(ˈɒksəzəʊl)
[ad. G. oxazol (Hantzsch & Weber 1887, in Ber. d. Deut. Chem. Ges. XX. 3119): see ox- 1, azo-, and -ole.]
a. A weakly basic, heterocyclic compound, O·CH:N·CH:CH , which is a volatile liquid. b. Any of the derivatives of this compound obtained by substituting for hydrogen.
| 1888 Jrnl. Chem. Soc. LIV. 574 Oxazoles are obtained by the condensation of α-halogen-ketones with amides. 1892 [see imidazole]. 1929 R. A. Gortner Outl. Biochem. xiv. 350 Polypeptides may be considered to enolize..yielding substituted imidazoles or substituted oxazoles. 1966 McGraw-Hill Encycl. Sci. & Technol. IX. 461/1 Oxazole is miscible with water and organic solvents. 1968 A. Albert Heterocyclic Chem. (ed. 2) vi. 289 Oxazole alkaloids have been isolated from flowering plants in the Rutaceae and Graminae, and oxazolidines (their reduced analogues) occur in cabbages. |