cortisone Biochem.
(ˈkɔːtɪzəʊn)
[See quot. 1949.]
A steroid hormone (C21H28O5) found in the adrenal cortex and prepared synthetically for use as an anti-inflammatory agent in rheumatoid arthritis, etc.
| 1949 N.Y. Times 1 June 33/8 The hormone..was named yesterday by its discoverer, Dr. Edward C. Kendall..as ‘cortisone’, an abbreviation of its long chemical name, 17-hydroxy-11 dehydrocortico-sterone. 1950 Lancet 28 Jan. 169/1 Hench's dramatic report on ‘Cortisone’ in rheumatoid arthritis has opened an entirely new field of work. 1952 [see corticosterone]. 1952 [see corticotrophin]. 1952 Sci. News XXIII. 7 Cortisone is secreted in minute quantities by the adrenal cortex of the suprarenal gland, which, as its name indicates, is situated above the kidneys. 1957 Oxf. Univ. Gaz. 3 Oct. 65/1 Trials of cortisone in the treatment of ulcerative colitis. 1964 [see cortisol]. |