oxalo-
combining element = oxal-, as oxaloˈacetate = oxalacetate s.v. oxal-; oxaloaˈcetic acid = oxalacetic acid s.v. oxal-; ˌoxalo-ˈnitrate, a salt of oxalic and nitric acid; oxaˈlosis Path. [-osis], a rare disorder of metabolism in which crystals and stones of calcium oxalate are deposited in the kidneys and elsewhere, often causing death during childhood as a result of renal failure; oxaloˈsuccinate, the anion, or an ester or salt, of oxalosuccinic acid; ˌoxalosucˈcinic acid, a tricarboxylic acid, HOOC·CO·CH(COOH)·CH2·COOH, which is an intermediate in the formation of α-ketoglutaric acid from isocitric acid in the Krebs cycle; oxalovinic (ˌɒksələʊˈvaɪnɪk) acid: a synonym of ethyloxalic acid, the acid oxalate of ethyl (C4H6O4 = C2H(C2H5)O4); hence oxalovinate (ɒksələʊˈvaɪnət), a salt of this acid, an ethyloxalate.
| 1943 Sumner & Somers Chem. & Methods of Enzymes xviii. 324 Malate, *oxaloacetate, or succinate could replace fumarate in reaction (c). 1962 S. G. Waley in A. Pirie Lens Metabolism Rel. Cataract 356 Another γ-keto acid that undergoes enzymatic decarboxylation is oxaloacetate. |
| 1937 Nature 18 Sept. 503/2 α-Ketoacids other than pyruvic, for example..*oxaloacetic or phenylpyruvic acid, may equally serve as acceptors for the amino group of glutamic acid. 1940 [see α-ketoglutarate s.v. keto- a]. 1968 Passmore & Robson Compan. Med. Stud. I. ix. 14/2 Acetyl-CoA reacts with oxaloacetic acid to produce citric acid. |
| 1873 Watts Fownes' Chem. (ed. 11) 427 A basic *oxalo⁓nitrate is obtained by adding ammonium oxalate to the oxynitrate. |
| 1952 Ying Chou & Donohue in Pediatrics X. 660 (heading) *Oxalosis. Possible ‘inborn error of metabolism’ with nephrolithiasis and nephrocalcinosis due to calcium oxalate as the predominating features. 1973 N. M. R. Buist et al. in Forfar & Arneil Textbk. Pediatrics xix. 1171/2 Treatment of oxalosis includes alkalinization of the urine, dietary restriction of calcium and a large fluid intake. |
| 1911 Chem. Abstr. V. 3240 Tri-Et *oxalosuccinate..is best prepared by means of EtOK. 1962 S. G. Waley in A. Pirie Lens Metabolism Rel. Cataract 355 In the citric acid cycle..two molecules of CO2 are formed per turn of the cycle; one comes from oxalosuccinate, a β-keto acid. |
| 1925 Chem. Abstr. XIX. 4423 (Index), *Oxalosuccinic acid, triethyl ester. 1948 Jrnl. Biochem. CLXXIV. 144 The instability of oxalosuccinic acid makes an accurate estimation of this constant rather difficult. 1966 F. A. Robinson Vitamin Co-Factors of Enzyme Syst. viii. 541 In this organism [sc. E. coli], biotin appears to function in the conversion of oxalosuccinic acid into α-ketoglutaric acid. |
| 1838 T. Thomson Chem. Org. Bodies 172 *Oxalo⁓vinic acid..was discovered by Mitscherlich... It decomposes carbonates of barytes and lime, forming soluble *oxalo⁓vinates capable of crystallizing. From oxalovinate of barytes it is easy to obtain pure oxalovinic acid. |