luteinization Physiol.
(ˌl(j)uːtiːnaɪˈzeɪʃən)
[f. lutein + -ization.]
The formation of lutein in the cells that remain of the Graafian follicle after expulsion of the ovum, during which process the follicle is converted into the corpus luteum; the formation of a corpus luteum.
| 1929 Anatomical Rec. XLIII. 239 (heading) The origin of the corpus luteum in the rat as indicated by studies upon the luteinization of the cystic follicles. 1931 Amer. Jrnl. Physiol. XCVII. 292 It [sc. the luteinizing hormone] does, however, cause luteinization of the follicles which are produced by the gonad stimulator. 1967 G. S. Richardson Ovarian Physiol. ii. 22 Increased follicular growth without luteinization or corpus-luteum formation. 1968 Passmore & Robson Compan. Med. Stud. I. xxxvii. 18/2 Following ovulation and subsequent luteinization of the follicle, oestrogen synthesis is supplemented by the production of progestagens. |
Hence ˈluteinize v. trans., to cause (a tissue associated with the corpus luteum) to form lutein; ˈluteinized ppl. a.; ˈluteinizing ppl. a. and vbl. n.; luteinizing hormone, a glyco-protein hormone secreted by the adenohypophysis which in the female helps to induce ovulation and brings about the formation of the corpus luteum, and in the male promotes the secretion of androgen by acting on the Leydig cells of the testis (abbrev. LH (L 7)).
| 1929 Anatomical Rec. XLIII. 242 The cells of either the granulosa or the theca have become luteinized. 1931 Amer. Jrnl. Physiol. XCVII. 291 (heading) The gonad stimulating and the luteinizing hormones of the anterior lobe of the hypophesis [sic]. Ibid. 294 This preparation..does luteinize the follicles produced by the gonad stimulating fraction. Ibid., The water soluble preparation contains primarily the gonad stimulating hormone with little or none of the luteinizing substance. Ibid. 295 Stimulation to luteinizing activity. 1935 Endocrinology XIX. 45 The ovary of the infantile rat can be luteinized to a much higher degree than was found in the above experiments with urine. 1966 Ann. Rev. Physiol. XXVIII. 61 Heavily luteinized ovaries. 1969 K. W. McKerns Gonads x. 279 Some 95 percent of the ovarian tissue consisted of luteinized cells. 1970 Sci. Jrnl. June 47/1 Three gonadotrophic hormones are produced by the anterior section of the pituitary gland: the mammotrophic hormone, prolactin, the follicle stimulating hormone (FSH) and the luteinizing hormone (LH). 1970 Nature 26 Sept. 1344/2 In the cyclic female albino rat, a release of pituitary luteinizing hormone (LH) occurs on the afternoon of proestrus. |