polyoma Microbiol.
(pɒlɪˈəʊmə)
[f. poly- + -oma.]
In full polyoma virus. A papovavirus that is endemic in mice without producing tumours but which can produce many kinds of tumour in young rodents.
| 1958 B. E. Eddy et al. in Proc. Soc. Exper. Biol. & Med. XCVIII. 848/1 A virus, which we shall refer to as SE polyoma virus, was recovered from tissue cultures inoculated with tumor material from mice and was shown to induce multiple tumors in mice..and hamsters. 1962 [see papovavirus]. 1962 Times 27 July 21/6 In many fully formed growths induced by the polyoma virus, no sign of the virus can be found under the electron microscope. 1967 Ambrose & Easty in E. J. Ambrose et al. Cancer Cell in Vitro v. 41 Several viruses will produce malignant transformations in vitro when grown on cells of animal origin, for example, polyoma virus, Rous sarcoma virus, and SV 40 virus. The polyoma transformation is the one most extensively studied. 1969 A. M. Campbell Episomes xiv. 169 Mammalian DNA viruses such as polyoma and SV 40 cause the formation of tumors. 1973 R. G. Krueger et al. Introd. Microbiol. xxviii. 699/1 All of the tumors induced by polyoma virus in various different mouse strains and hamsters have a common antigen. 1975 Melief & Schwartz in F. F. Becker Cancer I. v. 123 The polyoma virus, which commonly infects both wild and laboratory mice.., does not produce tumors under natural conditions even though it is potentially very oncogenic. |