pathogenesis Med. and Path.
(pæθəʊˈdʒɛnɪsɪs)
[f. patho- + genesis.]
Production or development of disease; the process or manner of origination of a disease or bodily affection. Also pathogenesy (-ˈdʒɛnɪsɪ), pathogeny (pəˈθɒdʒɪnɪ), in same sense. So pathogenetic (-dʒɪˈnɛtɪk), pathogenic (-ˈdʒɛnɪk), pathogenous (pəˈθɒdʒɪnəs) adjs., producing, or relating to the production of, disease or bodily affection; pathogenicity (-dʒɪˈnɪsɪtɪ), the quality or capacity of producing disease; pathogeˈnetically, pathoˈgenically advs., as regards pathogenesis.
| 1876 tr. Wagner's Gen. Pathol. (ed. 6) 235 Not more certainly known is the *pathogenesis of the..acute dropsies..in tropical countries. 1897 Trans. Amer. Pediatric Soc. IX. 168j, Heredity is a most potent factor in all pathogenesis. 1898 Allbutt's Syst. Med. V. 1015 A contracted mitral orifice, evidently of slow pathogenesis. |
| 1882 A. C. Pope Homœopathy 41 A medicine, the *pathogenesy of which may bear a likeness to several forms of disease. 1887 Homeop. World 1 Nov. 490 The medicine has in its pathogenesy many symptoms of a neuralgic character. |
| 1838 H. Dunsford (title) The *Pathogenetic Effect of some of the Principal Homœopathic Remedies, translated from the German. 1899 Allbutt's Syst. Med. VI. 249 Infective emboli containing pathogenetic bacteria. |
| 1928 Amer. Jrnl. Path. IV. 632 Primary and secondary contracted kidneys in this respect are *pathogenetically identical. 1972 Aronson & Elliott Ocular Inflammation xi. 258/2 Pathogenetically, the diffuse fundus lesion presents as a disseminated metastatic choroiditis,..relatively early in life. |
| 1852 Th. Ross Humboldt's Trav. II. xx. 246 In the torrid zone..the people multiply *pathogenic causes at will. 1896 Allbutt's Syst. Med. I. 70 Under ordinary pathogenic conditions suppuration is induced by the growth of micro-organisms within the tissues. |
| 1904 Brit. Med. Jrnl. 10 Sept. 559 The cells *pathogenically affected by a toxin may not be the cells of origin or antitoxin. |
| 1899 A. C. Houston in Nature 7 Sept. 434/2 Allowing..virulent bacilli..to develop and display their full power of *pathogenicity. |
| 1886 Sci. Amer. 4 Dec. 354/3 The distinction of the bacteria into *pathogenous and non-pathogenous is here unimportant. |
| 1842 Dunglison Med. Lex., *Pathogeny, the branch of pathology, which relates to the generation, production, and development of disease. 1898 J. Hutchinson in Arch. Surg. IX. No. 36. 351 It would be unwise to assume that in that fact its whole pathogeny is included. |