cybrid, n. Cell Biol.
Brit. /ˈsʌɪbrɪd/, U.S. /ˈsaɪbrɪd/
[Blend of cytoplasmic adj. and hybrid n.]
A hybrid cell produced artificially by the fusion of two cells of which one lacks a nucleus; an organism developed from such a cell. Also attrib. or as adj.
| 1974 C. L. Bunn et al. in Proc. National Acad. Sci. U.S.A. 71 1681/1 A chloramphenicol-resistant mutant..was enucleated and fused with a nucleated chloramphenicol-sensitive mouse cell line. Resultant fusion products, cytoplasmic hybrids (or ‘cybrids’), were selected as resistant to chloramphenicol. 1988 Jrnl. Cell Sci. 89 253 (title) Induction of cybrid strains of Tetrahymena thermophila by electrofusion. 1998 R. Tpfer & N. Martini in A. Altman Agric. Biotechnol. vii. 163 The less related the species involved, the smaller the chances of a successful regeneration of fertile cybrid plants. 2006 Daily Tel. 13 Jan. 10/5 The use of cybrids and chimeras is ‘a grey area’ in terms of current regulations. |