▪ I. toxo-1
(tɒksəʊ)
before a vowel tox-, combining form repr. Gr. τόξον bow, in toxocampid, toxodon, toxology, toxophilite, etc., q.v.
▪ II. toxo-2
used as combining form of toxin (cf. toxi-) or instead of toxico-, in recent scientific terms, chiefly of pathology or physiological chemistry. toxo-inˈfectious a., involving infection by a toxin: = toxi-infectious (toxi-). toxoˈpeptone, (a) a poisonous substance, of the nature of a peptone, found in cultures of cholera bacillus (Cent. Dict. Suppl.); (b) = peptotoxin. ˈtoxophil (-fɪl) a. [Gr. -ϕιλος loving], having affinity for a toxin. ˈtoxophore (-fɔə(r)) [ad. G. toxophor adj. (P. Ehrlich 1898, in Deutsch. med. Wochenschr. 22 Sept. 599/2)], toxophoric (-ˈfɒrɪk), toxophorous (-ˈɒfərəs) adjs. [Gr. -ϕορος bearing, carrying], poison-bearing; applied to a particular group of atoms in the molecule of a toxin to which its toxic properties are due; also toxophore n., a toxophoric group. toxophylaxin (-fɪˈlæksɪn) [Gr. ϕύλαξ guard, protector], toxosozin (-ˈsəʊzɪn) [Gr. σώζειν to save], names for defensive proteins or antitoxins (see quots.). toxoprotein (-ˈprəʊtiːɪn), a toxic protein, or mixture of a toxin and a protein.
| 1907 Med. Record 17 Aug. 279 The original cause of the lack of coagulation may be *toxoinfectious, or due to marked congestion. |
| 1896 Allbutt's Syst. Med. I. 526 Scholl, growing the vibrio, in eggs, obtained a *toxo-peptone. |
| 1902 Vaughan & Novy Cellular Toxins (ed. 4) 182 The body cells must possess *toxophil side chains. By this we mean that.. there are groups of atoms which may combine with bacterial toxins. |
| 1899 *Toxophore [see haptophore]. 1900 Lancet 18 Aug. 528/1 The toxophore group of the toxin molecule being much less stable than the haptophore group was much more easily destroyed. 1903 Brit. Med. Jrnl. 21 Mar. 654 The other atomic group is toxophore, namely, is the cause of the specific toxic action. 1951 Kirk & Othmer Encycl. Chem. Technol. VII. 121 In World War I, derivatives of trivalent arsenic received considerable attention, the structure {b1}As{b2} being considered a toxophore. |
| 1902 Brit. Med. Jrnl. 29 Mar. 785 The toxin molecule..must possess a second group which he [Ehrlich] calls the *toxophoric group. 1904 Ibid. 10 Sept. 574 Although the toxophoric group may be similar, the haptophor is dissimilar. |
| 1902 Encycl. Brit. XXVI. 65/1 In the molecule of toxin there are at least two chief atom groups—one, the ‘haptophorous’, by which the toxin molecule is attached to the cell protoplasm; and the other the ‘*toxophorous’, which has a ferment-like action on the living molecule, producing a disturbance which results in the toxic symptoms. |
| 1899 Syd. Soc. Lex., *Toxophylaxin, a defensive proteid produced in the body of an animal which has acquired immunity for a given infectious disease, and which has the power of rendering inert the toxic products of the pathogenic micro-organisms to which the condition was due. |
| 1896 Allbutt's Syst. Med. I. 523 The *toxo-proteins in reality are mixtures of albuminous, proteid, or albuminoid bodies with the true toxins. |
| 1899 Syd. Soc. Lex., *Toxosozin, a defensive proteid found in the body of a normal animal which has the power of protecting itself to a greater or less degree against micro-organisms and their products. |