solapsone Pharm.
(səˈlæpsəʊn)
[f. soluble a. + d)apsone, name of a drug of which solapsone is a more soluble derivative (f. di(paminophenyl)sulphone).]
A white powder given as tablets or by injection of an aqueous solution for the treatment of leprosy; the hydrated tetrasodium salt of di(p-3-phenyl-1, 3-disulphopropylamino)phenylsulphone, C30H28N2O14S5Na4.xH2O.
| 1952 Brit. Pharm. Codex Suppl. 66 Solapsone consists mainly of the tetrasodium salt. 1959 R. G. Cochrane Leprosy in Theory & Practice xvii. 212 The following sulphone drugs are those most commonly employed in the treatment of leprosy: (a) the parent sulphone..Dapsone (B.P.)..(b) Sulphetrone (Solapsone (B.P.)) administered orally or parenterally; [etc.]. 1974 R. M. Kirk et al. Surgery ii. 23 Specific treatment [of leprosy] is with dapsone..or solapsone (Sulphetrone) given orally, or by injection,..twice weekly. 1977 Martindale's Extra Pharmacopoeia (ed. 27) 1505/1 In general, the results with solapsone have not been impressive and it has been superseded by more active drugs. |