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colocynthin

colocynthin Chem.
  (kɒləˈsɪnθɪn)
  [see -in.]
  The bitter principle of colocynth, resembling a semi-transparent resin, and readily soluble in alcohol.

1830 Lindley Nat. Syst. Bot. 193. 1840 Henry Elem. Chem. II. 333 It contains the bitterness of the colocynth, and appears..to be a particular principle, for which he proposes the name of colocyntine. 1876 Bartholow Mat. Med. (1879) 481 Colocynthine is a very powerful cathartic.

Oxford English Dictionary

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