decarboxylate, v. Chem.
(diːkɑːˈbɒksɪleɪt)
[Back-formation from next.]
a. trans. To remove a carboxyl group from. b. intr. To lose a carboxyl group, to undergo decarboxylation. Hence decarˈboxylated, decarˈboxylating ppl. adjs.
| 1922 Jrnl. Biol. Chem. L. 132 Are all strains of colon bacilli capable of decarboxylating histidine in our standard medium? 1930 Biochem. Jrnl. XXIV. 262 It is necessary to employ a decarboxylating reagent. 1946 Nature 27 July 132/1 The carboxyl group..is very unstable and in the presence of alkali readily loses carbon dioxide, forming a decarboxylated compound. 1959 A. Albert Heterocyclic Chem. vii. 269 Dehydracetic acid undergoes ring-opening to aceto-acetylacetone-3-carboxylic acid: this decarboxylates to acetoacetylacetone which cyclizes to 2:6-dimethyl-γ-pyrone. 1962 S. G. Waley in A. Pirie Lens Metabolism Rel. Cataract 354 Only certain carboxylic acids..decarboxylate readily non-enzymatically. 1964 W. G. Smith Allergy & Tissue Metabolism iii. 36 Mast cells can decarboxylate histidine at an appreciable rate. |