sulindac, n. Pharm.
(sʌˈlɪndæk)
[f. sulph- + indene n. + acetic a., elements of the systematic name.]
A yellow crystalline powder, C20H17FO3S , with analgesic, anti-inflammatory, and antipyretic properties, given in tablet form in the treatment of arthritis and other musculoskeletal disorders.
| 1975 WHO Chron. XXIX. iii. Suppl. 21 Sulindac. 1975 Arthritis & Rheumatism XVIII. 411/2 These data suggest that sulindac is a safe and effective agent in the therapy of ankylosing spondylitis. 1977 Lancet 9 Apr. 804/2 Sulindac is a promising new agent for the management of painful arthritic disorders. 1983 Oxf. Textbk. Med. II. xvi. 53/1 The gastric irritation of sulindac is reduced by its conversion in the body to more active metabolites. |