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vacuolation

vacuolation
  (ˌvækjuːəˈleɪʃən)
  [f. next: cf. vacuolated ppl. a. and -ation.]
  The formation of vacuoles; change to a vacuolar state.

1858 Carpenter Veg. Phys. §318 In other cases it would appear that a number of cells are formed by a process of vacuolation. 1881 Mivart Cat 329 Vacuolation—denoting the spontaneous resolution of part of a more or less dense structure in such a way as to give rise to a cavity or cavities within it. 1899 Allbutt's Syst. Med. VI. 508 Vacuolation of the nerve-cell is peculiarly frequent in senile brain atrophy.

Oxford English Dictionary

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