sulphæmoglobin Biochem. and Med.
(ˌsʌlfhiːməʊˈgləʊbɪn)
Also sulph-hæmoglobin, -hemoglobin, (U.S.) sulfhemo-.
[f. sulph- + hæmoglobin.]
A sulphur-containing derivative of hæmoglobin, produced by its reaction with soluble sulphides or sulphides absorbed from the alimentary tract, and giving rise to the greenish discoloration found in putrefying cadavers.
| 1896 A. Bruce tr. Thoma's Text-bk. Gen. Path. I. iii. 43 In poisoning by charcoal fumes, carbonic-oxide-hæmoglobin is formed, and in poisoning by sulphuretted hydrogen, sulph-hæmoglobin or sulph-hæmatin. 1908 Hall & Defren tr. Abderhalden's Text-bk. Physiol. Chem. xxiv. 561 This green shade is due to the formation of sulph⁓hemoglobin, which, however, has never been prepared in a pure state. 1947 K. Simpson Forensic Med. xxviii. 314 Sulphaemoglobin forms naturally as post-mortem decomposition sets in. 1980 Amer. Jrnl. Physiol. CCXXXVIII. H745/2 This report concerns a method for ‘labeling’ red blood cells..by the formation of sulfhemoglobin. |
Hence ˌsulphæmoglobiˈnæmia [Gr. αἷµα blood], the presence of sulphæmoglobin in the blood, caused by drug-potentiated absorption of hydrogen sulphide from the alimentary tract, or direct assimilation of the sulpha group from any sulphonamide.
| 1910 Jrnl. Amer. Med. Assoc. 17 Dec. 2181/2 The patient was observed for some weeks, and as the ordinary blood examination failed to reveal any polycythemia or other abnormality to account for the condition, a tentative diagnosis of sulphemoglobinemia was made. 1961 A. S. MacNalty Brit. Med. Dict. 1373/2 It [sc. sulphæmoglobin] is produced under the influence of many substances such as nitrates, chlorates, nitrites..etc., causing enterogenous cyanosis or sulphaemoglobinaemia. 1980 Amer. Jrnl. Clin. Path. LXXIII. 245/1 In one specimen, marked methemoglobinemia and sulfhemoglobinemia were also demonstrated. |