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theriacle

theˈriacle Obs.
  Forms: 5 tiriacle, 6 tyriakle, 7 theriacle, -cal.
  [a. OF. tiriacle, ter(i)acle (15th c. in Godef. Compl.), beside OF. triacle (12th c.); popular alterations of tiriaque, thériaque, theriac: see also treacle.]
  = theriac, treacle n. 1.

c 1400 Mandeville (Roxb.) xxi. 94 Tiriacle may noȝt helpe ne nan oþer medecyne. 1561 Hollybush Hom. Apoth. 29 Geue him..a penyweyght of fyne Tyriakle. 1647 Trapp Comm. Acts xxviii. 5 A wholesome theriacle.., or treacle, as we call it. 1681 tr. Willis' Rem. Med. Wks. Vocab., Theriacal, or treacle, a medicine..invented against poysons. 1730–6 Bailey (folio), Theri{p}aca, Theri{p}ace, Theri{p}acle, Treacle.

Oxford English Dictionary

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