Koplik Med.
(ˈkɒplɪk)
[The name of Henry Koplik (1858–1927), U.S. pædiatrician.]
Koplik('s) spot: a small greyish-yellow spot, usually with a red halo, occurring on the bucal mucosa (or sometimes on the intestinal mucosa) in the early stages of measles.
| 1899 Med. News (N.Y.) LXXIV. 734/2 Koplik's spots were seen on the inner surface of the cheeks and under lip. 1939 Duval & Schattenberg Textbk. Path. ix. 284 Microscopically the macule or Koplik spot is a dense central collection of lymphocytes surrounded by tissue that is edematous and hyperemic. 1948 H. Pinkerton in W. A. D. Anderson Path. xv. 359 Koplik spots have been described in fatal cases in the intestinal mucosa. 1970 Hornstein & Gorlin in Gorlin & Goldman Thoma's Oral Path. (ed. 6) II. xvii. 756/2 Koplik's spots result from superficial necrosis of the mucosa and disappear after two to six days. |